Patents Assigned to Microbiological Research Authority (MRA) acting through the Centre for Applied Microbiology and Research (CAMR)
  • Anaerobe targeted enzyme-mediated prodrug therapy
    Patent number: 6416754
    Abstract: A genetically-engineered anaerobic organism is provided which, under anaerobic conditions present in a solid tumor, produces an enzyme capable of catalyzing the conversion of a prodrug to its highly cytotoxic product in situ and methods of treating tumors using same.
    Type: Grant
    Filed: July 23, 1996
    Date of Patent: July 9, 2002
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Microbiological Research Authority (MRA) acting through the Centre for Applied Microbiology and Research (CAMR)
    Inventors: John Martin Brown, Nigel P. Minton, Amato Giaccia