Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.
Type:
Grant
Filed:
May 19, 2021
Date of Patent:
September 13, 2022
Assignee:
Microbiotica Limited
Inventors:
Matthew Robinson, Trevor Lawley, Michael Romanos, Kevin Vervier, Simon Harris, Ghaith Bakdash, Amy Popple, Dominika Klisko
Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.
Type:
Grant
Filed:
May 19, 2021
Date of Patent:
July 5, 2022
Assignee:
Microbiotica Limited
Inventors:
Matthew Robinson, Trevor Lawley, Michael Romanos, Kevin Vervier, Simon Harris