Patents Assigned to Microcaps AG
  • Patent number: 12564820
    Abstract: A device for generating a dispersion of a first phase in a second phase includes a first inlet opening into a first chamber and being configured to supply a first phase and a second inlet opening into a second chamber and being configured to supply a second phase. A dispersion outlet is configured to collect the dispersion of the first phase in the second phase. A membrane separates the first and second chamber. The membrane includes a first side facing the first chamber and a second side facing the second chamber. Multiple channels extending from the first side to the second side of the membrane are configured to provide a fluidic connection between the first and second chamber. Each channel includes a channel inlet arranged on the first side of the membrane and a channel outlet arranged on the second side of the membrane.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: March 3, 2026
    Assignees: Microcaps AG, Eidgenossische Technische Hochschule Zurich (ETH) Zurich
    Inventors: Nicolas Sollich, Michael Hagander, Alessandro Ofner
  • Patent number: 12472479
    Abstract: Disclosed herein is a method for generating capsules with a hydrogel matrix. The method includes the steps: providing in a first chamber a dispersed aqueous phase, the dispersed aqueous phase including water and a hydrogel matrix-forming agent, in which the hydrogel matrix-forming agent is configured to form a hydrogel matrix upon exposure to a gelation inducer; providing in a second chamber a continuous oil phase, the continuous oil phase including oil and at least one first surfactant. The first and second chambers are fluidic connected by one or more channels, preferably by micro-channels. The method further includes: guiding the dispersed aqueous phase from the first chamber through the one or more channels into the second chamber to form an emulsion or dispersion of the dispersed aqueous phase in the continuous oil phase and exposing the hydrogel matrix-forming agent to a gelation inducer to form capsules with a hydrogel matrix.
    Type: Grant
    Filed: February 21, 2022
    Date of Patent: November 18, 2025
    Assignee: Microcaps AG
    Inventors: Giulia Biffi, Konstantina Papadea, Vittoria Picece, Dmitriy Pivovarov
  • Publication number: 20230415116
    Abstract: Disclosed is a method for generating capsules with a matrix shell encasing an oil core. The method includes: providing in a first chamber a core-forming emulsion of an aqueous dispersed phase in an oil phase including water and a dissolved gelation-inducing agent, and a first surfactant; providing in a second chamber a second aqueous solution including water and a second surfactant; wherein the first chamber and the second chamber are fluidically connected by one or more channels; guiding the core-forming emulsion from the first chamber through the channel(s) into the second chamber to form a dispersion of the core-forming emulsion in the aqueous solution; mixing the dispersion with an aqueous shell-forming solution including water and a water soluble matrix-forming agent; and reacting the gelation-inducing agent and the matrix-forming agent in the formed dispersion to form capsules of a water insoluble matrix shell encasing an oil core.
    Type: Application
    Filed: November 15, 2021
    Publication date: December 28, 2023
    Applicant: Microcaps AG
    Inventors: Giulia Biffi, Luis Rozas, Nesrine Ben Hadj Youssef, Michael Diener