Abstract: This invention provides microfluidic devices that comprise a fluidics layer having microfluidic channels and one or more regulating layers that regulate the movement of fluid in the channels. The microfluidic devices can be used to mix one or more fluids. At least a portion of the fluidics layer can be isolated from the regulating layer, for example in the form of a shelf. Such isolated portions can be used as areas in which the temperature of liquids is controlled. Also provided are instruments including thermal control devices into which the microfluidic device is engaged so that the thermal control device controls temperature in the isolated portion, and a movable magnetic assembly including magnets with shields so that a focused magnetic field can be applied to or withdrawn from the isolated portion or any other portion of the microfluidic device. Also provided are methods of mixing fluids.
Type:
Application
Filed:
December 18, 2009
Publication date:
July 1, 2010
Applicant:
Microchip Biotechnologies, Inc., a California Corporation
Inventors:
Stevan B. JOVANOVICH, William D. Nielsen, Michael Recknor, Mary Trounstine
Abstract: The invention provides for devices and methods for interfacing microchips to cartridges and pneumatic manifolds. The cartridges, microchips, and pneumatic manifolds can be integrated with downstream preparation devices, such as thermal regulating devices and separation and analysis devices.
Type:
Application
Filed:
January 21, 2009
Publication date:
October 8, 2009
Applicant:
Microchip Biotechnologies, Inc.
Inventors:
Mattias Vangbo, William D. Nielsen, Lullu I. Blaga, Seth Stern, Joanne Horn, Michael Van Nguyen, Stevan B. Jovanovich
Abstract: Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.
Type:
Application
Filed:
February 2, 2007
Publication date:
January 17, 2008
Applicant:
Microchip Biotechnologies, Inc.
Inventors:
Stevan Jovanovich, Iuliu Blaga, David Rank
Abstract: Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.
Type:
Application
Filed:
September 15, 2005
Publication date:
October 25, 2007
Applicant:
Microchip Biotechnologies, Inc.
Inventors:
Stevan Jovanovich, Iuliu Blaga, David Rank