Patents Assigned to Microdose Technologies, Inc.
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Publication number: 20080202514Abstract: A dry powder inhaler has a vibrator coupled to a blister filled with a dry powder drug substance. One or more of drug ejection apertures in the blister are substantially opposite the vibrator. One or more air intake apertures in the blister are not opposite the vibrator. Upon vibration of the vibrator, the drug substance is deaggregated, aerosolized, and ejected from the drug ejection apertures for inhalation by a patient.Type: ApplicationFiled: February 28, 2007Publication date: August 28, 2008Applicant: MICRODOSE TECHNOLOGIES, INC.Inventors: LEO B. KRIKSUNOV, ANAND V. GUMASTE
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Patent number: 7404968Abstract: Controlled quantities of powdered medication are formed in controlled release packages using electrostating metering. Also provided are combination medication therapy delivery packages comprising two or more active pharmaceuticals segregated from one another in a single delivery package.Type: GrantFiled: January 12, 2004Date of Patent: July 29, 2008Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste
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Patent number: 7343914Abstract: A child-sized adaptor for a DPI or MDI is provided. Also provided is a patient feedback mechanism for signaling and/or teaching proper inhaler use.Type: GrantFiled: September 6, 2002Date of Patent: March 18, 2008Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste
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Patent number: 7334577Abstract: A dry powder inhaler consisting of first chamber having an orifice for holding a dry powder and a gas, and a second chamber for receiving a deaggregated form of the dry powder and for communicating the deaggregated dry powder to a user. A synthetic jet drives the dry powder from the first chamber to the second chamber.Type: GrantFiled: March 1, 2006Date of Patent: February 26, 2008Assignee: Microdose Technologies, Inc.Inventors: Anand V. Gumaste, John Bowers
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Patent number: 7318434Abstract: A dry powder inhaler consisting of first chamber having an orifice for holding a dry powder and a gas, and a second chamber for receiving a deaggregated form of the dry powder and for communicating the deaggregated dry powder to a user. A synthetic jet drives the dry powder from the first chamber to the second chamber.Type: GrantFiled: February 17, 2005Date of Patent: January 15, 2008Assignee: Microdose Technologies, Inc.Inventors: Anand V. Gumaste, John Bowers
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Patent number: 7080644Abstract: A blister pack for use with inhalation therapy inhalers comprises an elongate bottom element having an overlying top element defining a plurality of spaced top crowned areas containing powder or liquid medications or drugs.Type: GrantFiled: June 25, 2001Date of Patent: July 25, 2006Assignee: Microdose Technologies, Inc.Inventor: Anand V. Gumaste
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Patent number: 6923979Abstract: Uniform portions of fine powders are deposited on a substrate by electrostatic attraction in which the charge of the electric field and polarity of the charged particles are varied repeatedly to form a buildup of powder on the carrier surface.Type: GrantFiled: April 27, 1999Date of Patent: August 2, 2005Assignee: Microdose Technologies, Inc.Inventors: Richard Fotland, John Bowers, William Jameson
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Patent number: 6702683Abstract: Controlled quantities of powdered medication are formed in controlled release packages using electrostating metering. Also provided are combination medication therapy delivery packages comprising two or more active pharmaceuticals segregated from one another in a single delivery package.Type: GrantFiled: January 11, 2002Date of Patent: March 9, 2004Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste
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Publication number: 20030041859Abstract: A child-sized adaptor for a DPI or MDI is provided. Also provided is a patient feedback mechanism for signaling and/or teaching proper inhaler use.Type: ApplicationFiled: September 6, 2002Publication date: March 6, 2003Applicant: MicroDose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste
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Patent number: 6428809Abstract: Controlled quantities of powdered medication are formed in controlled release packages using electrostating metering. Also provided are combination medication therapy delivery packages comprising two or more active pharmaceuticals segregated from one another in a single delivery package.Type: GrantFiled: August 18, 1999Date of Patent: August 6, 2002Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste
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Patent number: 6152130Abstract: An fluid sensor to activate and control various components of an inhalation device. The fluid sensor includes an acoustic element, such as a microphone, positioned within said inhalation device to detect fluid within the device and output signals representative of the frequency and/or amplitude of the fluid. These signals control and activate an electrostatic plate and/or a high frequency vibrator.Type: GrantFiled: June 12, 1998Date of Patent: November 28, 2000Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste, Scott Fleming
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Patent number: 6142146Abstract: A dry powder inhaler comprises a first chamber in which a dry powder may be deaggregated by a vibrator and separated by size, and a second chamber in which the size-separated deaggregated powder may be picked up by an air stream and carried for introduction into a patient. Electronic circuitry is included for controlling dosing.Type: GrantFiled: June 12, 1998Date of Patent: November 7, 2000Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste
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Patent number: 6026809Abstract: An inhaler that utilizes vibration to facilitate suspension of powder into a gas is provided. One embodiment of the inhaler includes a piezoelectric vibrator for vibrating the powder. A controller is provided for controlling supply of actuating electricity to the vibrator so as to cause the powder to vibrate in such a way as to optimally suspend at least a portion of the powder into the gas. The controller may include a user-actuable control for permitting the user to select the vibration frequencies and/or amplitudes for optimally suspending in the gas the type of powder currently being used in the inhaler.Type: GrantFiled: January 25, 1996Date of Patent: February 22, 2000Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste
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Patent number: 5960609Abstract: Electrostatic phototechnology is used to package microgram quantities of fine powders such as drugs in discrete capsule and tablet form. An electrostatic "image" having a given size and charge density is exposed to ionized drug powder to attract a known amount of drug to the image. The resultant drug "image", is then transferred to a an open ended capsule, a partially formed tablet or edible wafer or belt. The capsule is then sealed, i.e. by capping, or the tablet finished.Type: GrantFiled: June 12, 1998Date of Patent: October 5, 1999Assignee: Microdose Technologies, Inc.Inventors: Andrew L. Abrams, Anand V. Gumaste