Abstract: The present invention provides novel crystalline polymorphic forms of MDT-637, in particular, crystalline polymorphic forms with physicochemical properties specifically suited for drug production, amorphous formation, composite form, and methods of preparation thereof. The novel polymorphs described herein are useful for the treatment of respiratory disease, such as disease caused by respiratory syncytial virus.
Type:
Grant
Filed:
June 28, 2013
Date of Patent:
May 26, 2015
Assignee:
MICRODOSE THERAPEUTX
Inventors:
Robert O. Cook, Eugene R. Reynolds, Boris Shekunov, Siead I. Zegar