Abstract: A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.
Type:
Grant
Filed:
February 21, 2013
Date of Patent:
April 26, 2016
Assignees:
Lockheed Martin Corporation, MICROLAB DIAGNOSTICS, INC.
Inventors:
Michael Egan, Brian Root, Orion N. Scott, Douglas J. South, Joan Bienvenue, Paul Kinnon, James Landers, David Saul, An-Chi Tsuei, Jason Hayes, Matthew Springer, Matthew Solomon, Peter van Ruijven
Abstract: A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.
Type:
Application
Filed:
June 19, 2015
Publication date:
October 8, 2015
Applicants:
LOCKHEED MARTIN CORPORATION, MICROLAB DIAGNOSTICS, INC.
Inventors:
Michael E. EGAN, Brian Root, Orion N. Scott, Douglas J. South, Joan M. Bienvenue, Paul Kinnon, James Landers, David Saul, An-Chi Tsuei, Jason Hayes, Matthew Springer, Matthew Solomon, Peter Van Ruijven
Abstract: A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.
Type:
Application
Filed:
February 21, 2013
Publication date:
August 22, 2013
Applicants:
MICROLAB DIAGNOSTICS, INC., LOCKHEED MARTIN CORPORATION
Inventors:
LOCKHEED MARTIN CORPORATION, MICROLAB DIAGNOSTICS, INC.