Abstract: An endoscope in which a reusable part is inserted into a sheath of a single-use portion that includes a needle with an imaging module at its tip and a part of the reusable portion that is not covered by the sheath is covered with a flexible cap that initially was sterile and covered the open end of the sheath, whereby the entire reusable portion is covered and sealed from the environment by the cap and the sheath during a medical procedure.

Abstract: Systems and methods are configured for combined fluorescence imaging and white light imaging of tissue such as during surgical endoscopic procedures. A chip-on-tip type endoscope can be equipped with both white light and blue light LEDs. A single camera or dual cameras are configured with backside illuminated CMOS image sensor(s) to receive and process the white light and fluorescence images. The light sources, image sensors and image processing circuitry are configured to synchronously emit light and record pixels for visible white light and fluorescence frames alternately. Global or quasi-global shuttering can be used on the image sensor(s). A modified color filter array and other filters can be provided to enhance fluorescence imaging capabilities. Insufflating gas clears debris from the camera field of view and aids in moving the cannula distally through a body passageway.

Abstract: An endoscope in which a reusable portion is inserted nearly all the way into a hollow, pistol-grip handle of a single-use portion and the protruding part of the reusable portion and an adjacent part of the handle are covered with a flexible and resilient cap. The same cap covers the open end of the handle when the single-use portion is shipped from a manufacturing site. At a user's facility, a health professional tears the pouch, removes the cap from the handle, inserts the reusable portion, and covers the distal end of the reusable portion and an adjacent part of the handle with the same cap. Typically, a remote display connects to the endoscope wirelessly or through a cable, with a connector that fits through a hole in the cap configured to keep fluids from entering around the connector. The wireless transmission preferably uses a proprietary protocol to preserve medical data confidentiality.

Abstract: A medical endoscopy/stereo colposcopy instrument is configured to selectively take stereo colposcopy images of a patient's uterus and endoscopy images of the patient's bladder or uterus. Any of the images can be white light images or images for a selected narrow wavelength band or fluorescence images. The images can be displayed individually or as spatially registered composite images to highlight selected features of the imaged anatomy. A cup-shaped device can be positioned at the patient's cervix and provided with a light source and a fluorescence camera module to monitor changes in fluorescence in response to a photoactivated substance.

Abstract: An endoscopic system includes a single-use portion and a multiple-use portion. The two portions can be mated and un-mated. The single-use portion includes an elongated cannula that has a bendable section near its distal end providing a “steerable” distal tip. The imaging system includes at least two separate cameras and two separate light sources. The camera and light sources are configured to simultaneously image a target object. By employing different illuminations, different filters and manipulating the spectral responses, different characteristics of the target object can be captured. According to some embodiments, a system processor can coordinate the cameras, the light sources and combine the resulting images to display to an operator an enhanced combined image the object.

Abstract: Systems and methods are configured for combined fluorescence imaging and white light imaging of tissue such as during surgical endoscopic procedures. A chip-on-tip type endoscope can be equipped with both white light and blue light LEDs. A single camera or dual cameras are configured with backside illuminated CMOS image sensor(s) to receive and process the white light and fluorescence images. The light sources, image sensors and image processing circuitry are configured to synchronously emit light and record pixels for visible white light and fluorescence frames alternately. Global or quasi-global shuttering can be used on the image sensor(s). A modified color filter array and other filters can be provided to enhance fluorescence imaging capabilities. Insufflating gas clears debris from the camera field of view and aids in moving he cannula distally through a body passageway.