Abstract: Systems and computer-implemented methods for microscope-based learning including providing a first menu on a GUI to allow a user to identify or view a cell category of interest on a digital slide image that is simultaneously displayed with the first menu on the GUI. The systems and methods further include providing a navigation system on the GUI to allow the user to navigate the digital slide image and select proportional x and y coordinates on the digital slide image. A second menu is also provided on the GUI to allow the user to identify a cell type for the selected proportional x and y coordinates. The systems and methods are capable of automatically determining if the cell type identified by the user matches a predetermined cell type within the x and y coordinates from a database. The systems and methods further indicate whether the identified cell type matches the predetermined cell type on the GUI and display a summary of the total matches on the GUI.