Patents Assigned to Microspherix LLC
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Patent number: 10994058Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: GrantFiled: November 26, 2019Date of Patent: May 4, 2021Assignee: MICROSPHERIX LLCInventor: Edward J. Kaplan
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Patent number: 10493181Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: GrantFiled: April 20, 2017Date of Patent: December 3, 2019Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 9636402Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: GrantFiled: May 13, 2015Date of Patent: May 2, 2017Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 9636401Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: GrantFiled: August 29, 2014Date of Patent: May 2, 2017Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 8821835Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: GrantFiled: June 13, 2013Date of Patent: September 2, 2014Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Publication number: 20130251777Abstract: A radiopaque brachytherapy seed for implantation into a subject includes a biocompatible component, a therapeutically active component including a non-radioactive drug, and a radiopaque marker. The biocompatible component is (a) physically associated with a therapeutically active component and (b) in contact with the radiopaque marker. The brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).Type: ApplicationFiled: December 14, 2012Publication date: September 26, 2013Applicant: MICROSPHERIX LLCInventor: Edward J. Kaplan
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Patent number: 8470294Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: GrantFiled: June 25, 2010Date of Patent: June 25, 2013Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 7922645Abstract: Systems, apparatus, components and methods are disclosed that allow the clinician to circumvent the pubic arch in instances where it interferes with insertion of instrumentation into the prostate or periprostatic tissue. The systems, apparatus and components disclosed herein employ structures, such as needles and trocars, of shape memory alloys, such as nickel-titanium (Ni—Ti) for the purpose of avoiding the pubic arch when accessing the prostate from the perineum.Type: GrantFiled: October 16, 2007Date of Patent: April 12, 2011Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 7776310Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: GrantFiled: September 19, 2003Date of Patent: August 17, 2010Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 7282020Abstract: Systems, apparatus, components and methods are disclosed that allow the clinician to circumvent the pubic arch in instances where it interferes with insertion of instrumentation into the prostate or periprostatic tissue. The systems, apparatus and components disclosed herein employ structures, such as needles and trocars, of shape memory alloys, such as nickel-titanium (Ni—Ti) for the purpose of avoiding the pubic arch when accessing the prostate from the perineum.Type: GrantFiled: April 22, 2002Date of Patent: October 16, 2007Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Publication number: 20040109823Abstract: A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible.Type: ApplicationFiled: September 19, 2003Publication date: June 10, 2004Applicant: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 6746661Abstract: A radiopaque brachytherapy seed for implantation into a subject includes a biocompatible component, a therapeutically active component including a non-radioactive drug, and a radiopaque marker. The biocompatible component is (a) physically associated with a therapeutically active component and (b) in contact with the radiopaque marker. The brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).Type: GrantFiled: May 18, 2001Date of Patent: June 8, 2004Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 6514193Abstract: A method for administering a therapeutically active component including a non-radioactive drug to a target tissue in a subject includes the steps of: (a) providing a brachytherapy seed having a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge); (b) providing a brachytherapy implantation instrument comprising at least one brachytherapy implantation needle having a bore having an interior diameter of less than about 2.Type: GrantFiled: May 18, 2001Date of Patent: February 4, 2003Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Publication number: 20020173689Abstract: Systems, apparatus, components and methods are disclosed that allow the clinician to circumvent the pubic arch in instances where it interferes with insertion of instrumentation into the prostate or periprostatic tissue. The systems, apparatus and components disclosed herein employ structures, such as needles and trocars, of shape memory alloys, such as nickel-titanium (Ni—Ti) for the purpose of avoiding the pubic arch when accessing the prostate from the perineum.Type: ApplicationFiled: April 22, 2002Publication date: November 21, 2002Applicant: Microspherix LLCInventor: Edward J. Kaplan
