Abstract: A composition of matter comprising a synthetic miR-135 molecule comprising a nucleic acid sequence of a miR-135b as set forth in SEQ ID NO: 37, and a complementary strand as set forth in SEQ ID NO: 40 is disclosed. A conjugate comprising a composition of matter comprising a synthetic miR-135 molecule and a cell-targeting moiety is also disclosed.
Type:
Application
Filed:
July 14, 2023
Publication date:
January 25, 2024
Applicants:
Yeda Research and Development Co. Ltd., miCure Therapeutics Ltd.
Inventors:
Alon CHEN, Sharon MANASHIROV, Andres Pablo MONTEFELTRO