Abstract: A nucleic acid molecule having a nucleotide sequence encoding a chimeric antigen receptor, where the nucleic acid molecule includes a segment encoding an extracellular domain, a segment encoding a transmembrane domain, and a segment encoding an intracellular domain. The segment encoding the extracellular domain includes a nucleotide sequence encoding an antigen binding region including a light chain variable region and a heavy chain variable region, and at least three codons in a nucleotide sequence encoding framework region 3 of the light chain variable region as defined by the Chothia method are codons encoding acidic amino acid residues.

Abstract: System for, and method of, monitoring airborne particulate, including particulate of the PM.sub.2.5 class. The system for monitoring airborne particulate includes an optical sensor to measure size characteristics of sampled airborne particulate and a humidity sensor to measure relative humidity. An adjusted airborne concentration value is then produced in response to the measured size characteristics and to the humidity measurement. According to one embodiment the optical sensor is implemented as a multi-wavelength nephelometer, e.g., two-wavelength nephelometer. According to another embodiment the humidity sensor is placed relatively near the optical sensing region and makes a relative humidity measurement.