Abstract: A method and a device for a microfluidic separation enhancement according to size of the particles to be separated are provided. An asymmetric obstacle in a shape of a cambered hydrofoil, placed at a downstream of a microfluidic channel increases a distance between particles of different sizes, wherein the particles have been partially separated at an upstream of the microfluidic channel, resulting an enhancement in the separation efficiency. Thus, microchannel length is decreased, resulting a decrease in hydraulic resistance and footprint of the microchannel.
Type:
Grant
Filed:
May 3, 2019
Date of Patent:
July 16, 2024
Assignee:
MIKRO BIYOSISTEMLER ELEKTRONIK SANAYI VE TICARET A.S.
Abstract: A microfluidic device is provided. The microfluidic device is used for an in vitro selective capture of biological entities suspended in a medium based on an immunoaffinity technique. The microfluidic device includes symmetric hydrofoil pillars arranged inside ellipse segments acting as a microfluidic channel, wherein the microfluidic channel provides a continuous change of attack angles between the symmetric hydrofoil pillars and the biological entities.
Type:
Grant
Filed:
August 6, 2019
Date of Patent:
July 16, 2024
Assignee:
MIKRO BIYOSISTEMLER ELEKTRONIK SANAYI VE TICARET A.S.
Inventors:
Begum Sen Dogan, Ender Yildirim, Ozge Zorlu, Ebru Ozgur
Abstract: A microfluidic device is provided. The microfluidic device is used for an in vitro selective capture of biological entities suspended in a medium based on an immunoaffinity technique. The microfluidic device includes symmetric hydrofoil pillars arranged inside ellipse segments acting as a microfluidic channel, wherein the microfluidic channel provides a continuous change of attack angles between the symmetric hydrofoil pillars and the biological entities.
Type:
Application
Filed:
August 6, 2019
Publication date:
March 10, 2022
Applicant:
MIKRO BIYOSISTEMLER ELEKTRONIK SANAYI VE TICARET A.S.
Inventors:
Begum SEN DOGAN, Ender YILDIRIM, Ozge ZORLU, Ebru OZGUR
Abstract: A method and a device for a microfluidic separation enhancement according to size of the particles to be separated are provided. An asymmetric obstacle in a shape of a cambered hydrofoil, placed at a downstream of a microfluidic channel increases a distance between particles of different sizes, wherein the particles have been partially separated at an upstream of the microfluidic channel, resulting an enhancement in the separation efficiency. Thus, microchannel length is decreased, resulting a decrease in hydraulic resistance and footprint of the microchannel.
Type:
Application
Filed:
May 3, 2019
Publication date:
March 10, 2022
Applicant:
MIKRO BIYOSISTEMLER ELEKTRONIK SANAYI VE TICARET A.S.