Patents Assigned to MIKROGEN GmbH
  • Patent number: 11169153
    Abstract: Herein disclosed is a method for the normalization of an immunological test, characterized in that the presence of a comparable amount of cells is determined by a sandwich ELISA test in which the capture antibody includes at least one antibody that binds to at least one keratin selected from among keratin 4, 5, 6, 8, 10, 13 and 18 and the detection antibody includes at least one antibody that binds to the selected keratin.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: November 9, 2021
    Assignee: Mikrogen GmbH
    Inventors: Isabel Koch, Oliver Boecher, Erwin Soutschek, Steven McNamara
  • Patent number: 10921323
    Abstract: The present invention relates to a method for the immunological diagnosis of a sample from a patient with a potential infection with an arbovirus, wherein a) a sample is brought into contact with a plurality of antigens that, separated from each other, are applied to a solid phase, wherein at least the following antigens are used: aa) the “non-structural protein 1” of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, bb) an “envelope protein” of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, cc) an “envelope protein” of a second arbovirus or an immunologically reactive part thereof having at least 8 amino acids, dd) the “non-structural protein 1” of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids and ee) an “envelope protein” of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids, b) the solid phase is washed to separate non-specific b
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: February 16, 2021
    Assignee: Mikrogen GmbH
    Inventors: Erwin Soutschek, Oliver Boecher, Christina Noelting
  • Publication number: 20190079091
    Abstract: The present invention relates to a method for the normalization of an immunological test characterized in that the presence of a comparable amount of cells is determined by a sandwich ELISA test wherein the capture antibody is at least one antibody which binds to at least one keratin selected from the group consisting of keratin 4, 5, 6, 8, 10, 13 and 18 and the detection antibody is at least one antibody which binds to said keratin.
    Type: Application
    Filed: July 28, 2016
    Publication date: March 14, 2019
    Applicant: Mikrogen GmbH
    Inventors: Isabel KOCH, Oliver BOECHER, Erwin SOUTSCHEK, Steven MCNAMARA
  • Publication number: 20180259523
    Abstract: The present invention relates to a diagnostic test for the detection of an E7 protein of a human papilloma virus in a biological sample wherein a sandwich ELISA as capture antibody at least two different rabbit monoclonal antibodies which bind to at least two different epitopes are used and as detection antibody at least two different polyclonal anti E7 antibodies are used.
    Type: Application
    Filed: October 30, 2015
    Publication date: September 13, 2018
    Applicants: Mikrogen GmbH, Österreichische Akademie der Wissenschaften
    Inventors: Pidder JANSEN-DÜRR, Oliver BÖCHER, Isabel KOCH, Erwin SOUTSCHEK
  • Patent number: 8580521
    Abstract: Devices are disclosed for serologically detecting an infection with human-pathogenic Yersinia ssp, wherein said device comprises at least one antigen selected from the group of antigens consisting of the following group: YopD, YopH, YopM, YopE, V-AG and YopN or a fragment of one of said antigens having at least eight consecutive amino acids and furthermore one of two proteins selected from MyfA and PsaA or fragments of one of said two proteins having at least eight consecutive amino acids.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: November 12, 2013
    Assignee: Mikrogen GmbH
    Inventor: Erwin Soutschek
  • Patent number: 8455210
    Abstract: The present invention relates to a method for the selective identification of Chlamydia trachomatis infections wherein the antigens CT017, CT098, CT318-L1 P, CT431-TARP, CT603-TSAP, and CT664 are used for the specific identification of Chlamydia trachomatis antibodies in samples from mammals. The method according to the invention facilitates the selective identification method of identification of Chlamydia trachomatis infections, in which no false positive results are generated by other Chlamydia species such as, for example, Chlamydia pneumoniae. The invention further relates to a biochip which has the aforementioned Chlamydia trachomatis-specific antigens for the identification of antibodies. The biochip with antigens according to the invention is suitable for multiparameter identification methods in particular.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: June 4, 2013
    Assignee: Mikrogen GmbH
    Inventors: Ulrike Simnacher, Vera Forsbach-Birk, Andreas Essig, Klaus-Ingmar Pfrepper
  • Publication number: 20110306515
    Abstract: Devices are disclosed for serologically detecting an infection with human-pathogenic Yersinia ssp, wherein said device comprises at least one antigen selected from the group of antigens consisting of the following group: YopD, YopH, YopM, YopE, V-AG and YopN or a fragment of one of said antigens having at least eight consecutive amino acids and furthermore one of two proteins selected from MyfA and PsaA or fragments of one of said two proteins having at least eight consecutive amino acids.
    Type: Application
    Filed: February 11, 2010
    Publication date: December 15, 2011
    Applicant: MIKROGEN GmbH
    Inventor: Erwin Soutschek