Patents Assigned to Milkhaus Laboratory
  • Publication number: 20100144602
    Abstract: The invention provides a method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
    Type: Application
    Filed: December 7, 2009
    Publication date: June 10, 2010
    Applicant: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 7629312
    Abstract: The invention provides a method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: December 8, 2009
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Publication number: 20080182789
    Abstract: Methods and compositions for treating pulmonary fibrosis are presented. Methods comprise administering compositions comprising DNA and streptolysin O to a subject in a manner so as not to effect gene transfer.
    Type: Application
    Filed: December 28, 2007
    Publication date: July 31, 2008
    Applicant: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Publication number: 20070270347
    Abstract: Method for administering nerve growth factor to treat various psychological conditions such as of depression, bi-polar disorders, anxiety disorders, panic attacks, agoraphobia, and attention deficit syndrome, and alleviate symptoms associated with premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), sleep disorders, tension headaches, and constipation that arise as complications from a psychological condition. Also provided are methods of treating constipation comprising administering nerve growth factor in amount effective to treat constipation. Pharmaceutical compositions for the treatment of constipation comprising nerve growth factor are also provided.
    Type: Application
    Filed: June 25, 2007
    Publication date: November 22, 2007
    Applicant: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 7196058
    Abstract: Method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: March 27, 2007
    Assignee: Milkhaus Laboratory, Inc.
    Inventors: John McMichael, Jean-Frederic Sauniere
  • Patent number: 7101847
    Abstract: The present invention is directed to methods of treating a chronic pelvic pain syndrome comprising the step of administering to a subject suffering from prostatis a chorionic gonadotropin or a pharmaceutically active fragment or derivative thereof in an amount effective to alleviate one or more symptoms of a chronic pelvic pain syndrome.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: September 5, 2006
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6998121
    Abstract: Method for administering streptolysin O to treat various connective tissue disorders in humans and animals such as Dupuytren's contracture, scleroderma, Peyronie's disease, mastistis in animals, and claudication due to peripheral arterial disease.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: February 14, 2006
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6989368
    Abstract: The present invention provides methods and compositions for promoting bone regeneration, comprising administration of calmodulin. The method of bone regeneration is applied to subjects having bone disorders characterized by decreased bone mass such as osteopenia and osteoporosis, as well as those suffering from non-union fractures.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: January 24, 2006
    Assignee: Milkhaus Laboratory, Inc.
    Inventors: John McMichael, Harry C. Gurney
  • Patent number: 6713058
    Abstract: The invention provides methods and compositions for alleviating the symptoms of neuropathic conditions with a pharmaceutical composition including an effective amount of anti-glutamic acid decarboxylase (anti-GAD) antibodies.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: March 30, 2004
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6592875
    Abstract: The present invention relates to a treatment for patients having Lyme disease by administering a composition comprising an Borrelia burgdorferi antigen at a sub-vaccine level effective to alleviate symptoms of Lyme disease.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: July 15, 2003
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Publication number: 20020115632
    Abstract: Methods for treating symptoms of asthma, allergies and otitis media in a patient, are presented. Methods comprise administering an effective amount of DNA to a subject in a manner so as not to effect gene transfer.
    Type: Application
    Filed: April 1, 2002
    Publication date: August 22, 2002
    Applicant: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6436401
    Abstract: The invention provides methods and compositions for alleviating the symptoms of diabetes with a pharmaceutical composition including a combination of anti-glutamic acid decarboxylase (anti-GAD) and anti-insulin antibodies.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: August 20, 2002
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6437093
    Abstract: A method for treatment of symptoms of a respiratory disease or pain in a subject comprising administering to said subject a Substance P in an amount effective to alleviate those symptoms.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: August 20, 2002
    Assignee: Milkhaus Laboratory, Inc.
    Inventors: Allan D. Lieberman, John McMichael
  • Patent number: 6383741
    Abstract: The present invention relates to a treatment for animals having canine distemper by administering a composition comprising an attenuated canine distemper virus a sub-vaccine virus level effective to alleviate symptoms canine distemper. The invention also provides a treatment for animals having canine distemper by administering a composition comprising an attenuated canine measles virus a sub-vaccine virus level effective to alleviate symptoms canine distemper.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: May 7, 2002
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6303127
    Abstract: The invention presents methods for the treatment of symptoms associated with diseases states including cardiomyopathy, Parkinson's Disease and degenerative liver disease including cirrhosis comprising treatment with an effective amount of a composition comprising beta-amyloid, streptolysin O, and growth hormone.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: October 16, 2001
    Assignee: Milkhaus Laboratory, Inc.
    Inventors: John McMichael, Harry C. Gurney
  • Patent number: 6294171
    Abstract: The invention provides methods and compositions for treating the symptoms of disease states associated with the presence of a toxin or infectious agent having the step of administering an antibody specific for the toxin or infectious agent at a dosage of less than 0.1 mg per day.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: September 25, 2001
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6174916
    Abstract: Methods and compositions are provided for alleviation of disease states involving plaque formation, such as are manifested in Alzheimer's Disease and other amyloid disorders, and arteriosclerotic disease. Methods for the treatment of herpes virus infections including chronic fatigue syndrome by administration of thimerosal are further provided by the invention.
    Type: Grant
    Filed: April 1, 1998
    Date of Patent: January 16, 2001
    Assignee: Milkhaus Laboratory, Ltd.
    Inventor: John McMichael
  • Patent number: 6156780
    Abstract: The present invention relates to a treatment for patients having fecal incontinence by administering a composition comprising histamine, serotonin or a combination thereof in an amount effective to alleviate symptoms of fecal incontinence.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: December 5, 2000
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6100244
    Abstract: Methods for treating symptoms of respiratory distress not associated with aberrant mucous accumulation in a patient, are presented. Methods comprise administering an effective amount of DNA to a subject in a manner so as not to effect gene transfer.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: August 8, 2000
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Patent number: 6096721
    Abstract: Methods for treating mucositis are presented. An effective amount of DNA is administered to a patient with mucositis sublingually in a manner that does not cause gene transfer but does cause a reduction in viscosity of mucous or sputum.
    Type: Grant
    Filed: March 10, 1998
    Date of Patent: August 1, 2000
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael