Patents Assigned to Millenium Pharmaceuticals
  • Identification of polycystic kidney disease gene, diagnostics and treatment
    Patent number: 5891628
    Abstract: The present invention relates to the identification of the autosomal dominant polycystic kidney disease (PKD) gene and high throughput assays to identify compounds that interfere with PKD activity. Interfering compounds that inhibit the expression, synthesis and/or bioactivity of the PKD gene product can be used therapeutically to treat polycystic kidney disease.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: April 6, 1999
    Assignees: Brigham and Women's Hospital, Millenium Pharmaceuticals
    Inventors: Stephen Reeders, Michael Schneider, Maria Alexandra Glucksmann