Patents Assigned to Millikelvin Technologies LLC
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Patent number: 10408895Abstract: A carrier for a sample of highly polarized material includes a shell having a radially exterior surface and a radially interior surface, and a sample of highly polarized material interiorly adjacent to the radially interior surface. The shell may be substantially cylindrical, and may be constructed from a magnetic or non-magnetic material. The sample of highly polarized material may comprise a methyl rotor group material. The sample of highly polarized material may comprise pyruvic acid or an acetic acid. The sample of highly polarized material may be co-axial with the cylindrical shell. The sample of highly polarized material may be bonded or frozen to the radially interior surface of the shell. The carrier may further comprise a wad of material that forms a volume and contacts an axially proximate end of at least one of the shell or the sample.Type: GrantFiled: March 14, 2014Date of Patent: September 10, 2019Assignees: Bruker Biospin Corporation, Millikelvin Technologies LLCInventors: Matthew Hirsch, Avrum Belzer, Neal Kalechofsky, Charles Monroe
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Patent number: 9714995Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses. In various illustrative methods, beneficial agents can be administered to samples or subjects to be studied. Some beneficial agents can include biomarkers, or precursors to biomarkers.Type: GrantFiled: March 13, 2014Date of Patent: July 25, 2017Assignee: Millikelvin Technologies LLCInventor: Neil Kalechofsky
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Patent number: 9606200Abstract: A method of providing a material sample in a state favorable to retaining spin polarization includes cooling a material sample from a temperature above a freezing point of the material sample down to a second temperature below the freezing point of the material sample; maintaining the sample at about the second temperature for a period of about several hours; and reducing temperature of the material sample to a third temperature lower than the second temperature to provide the material sample in a state favorable to retaining spin polarization, where the steps of cooling, maintaining and reducing are performed in the absence of an adulterant material. The method of providing a sample of pyruvic acid in a state favorable to retaining spin polarization may include cooling the sample of pyruvic acid in the absence of an adulterant material from a temperature above a freezing point of the sample of pyruvic acid down to less than about 200 Kelvin to provide the sample.Type: GrantFiled: January 22, 2014Date of Patent: March 28, 2017Assignees: Bruker Biospin Corporation, Millikelvin Technologies LLCInventors: James G. Kempf, Neal Kalechofsky, Melanie Rosay
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Patent number: 9014785Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.Type: GrantFiled: February 24, 2014Date of Patent: April 21, 2015Assignee: Millikelvin Technologies LLCInventors: Neal Kalechofsky, Mirko Hrovat
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Publication number: 20150061666Abstract: A method of providing a material sample in a state favorable to retaining spin polarization includes cooling a material sample from a temperature above a freezing point of the material sample down to a second temperature below the freezing point of the material sample; maintaining the sample at about the second temperature for a period of about several hours; and reducing temperature of the material sample to a third temperature lower than the second temperature to provide the material sample in a state favorable to retaining spin polarization, where the steps of cooling, maintaining and reducing are performed in the absence of an adulterant material. The method of providing a sample of pyruvic acid in a state favorable to retaining spin polarization may include cooling the sample of pyruvic acid in the absence of an adulterant material from a temperature above a freezing point of the sample of pyruvic acid down to less than about 200 Kelvin to provide the sample.Type: ApplicationFiled: January 22, 2014Publication date: March 5, 2015Applicants: Millikelvin Technologies LLC, Bruker Biospin CorporationInventors: James G. Kempf, Neal Kalechofsky, Melanie Rosay
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Publication number: 20140285192Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.Type: ApplicationFiled: March 13, 2014Publication date: September 25, 2014Applicant: Millikelvin Technologies LLCInventor: Neil Kalechofsky
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Publication number: 20140285191Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.Type: ApplicationFiled: March 13, 2014Publication date: September 25, 2014Applicant: Millikelvin Technologies LLCInventor: Neil Kalechofsky
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Publication number: 20140266197Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.Type: ApplicationFiled: March 13, 2014Publication date: September 18, 2014Applicant: Millikelvin Technologies LLCInventor: Neil Kalechofsky
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Publication number: 20140247047Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.Type: ApplicationFiled: February 24, 2014Publication date: September 4, 2014Applicant: Millikelvin Technologies LLCInventors: Neal Kalechofsky, Mirko Hrovat
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Patent number: 8703102Abstract: The present disclosure provides various methods and systems for manufacture, transport and delivery of material including highly polarized nuclei that is in a hyperpolarized state.Type: GrantFiled: September 10, 2010Date of Patent: April 22, 2014Assignee: Millikelvin Technologies LLCInventors: Neal Kalechofsky, Avrum Belzer
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Patent number: 8703201Abstract: The disclosure provides various methods and systems for providing hyperpolarized materials as well as the hyperpolarized materials so provided. In addition, methods of providing hyperpolarized materials, such as agents, to end users from a remote location are also provided.Type: GrantFiled: December 22, 2011Date of Patent: April 22, 2014Assignee: Millikelvin Technologies LLCInventors: Avrum Belzer, Neal Kalechofsky
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Publication number: 20130154643Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.Type: ApplicationFiled: February 11, 2013Publication date: June 20, 2013Applicant: Millikelvin Technologies LLCInventor: Millikelvin Technologies LLC
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Publication number: 20120114851Abstract: The disclosure provides various methods and systems for providing hyperpolarized materials as well as the hyperpolarized materials so provided. In addition, methods of providing hyperpolarized materials, such as agents, to end users from a remote location are also provided.Type: ApplicationFiled: December 22, 2011Publication date: May 10, 2012Applicant: Millikelvin Technologies LLCInventors: Neal Kalechofsky, Avrum Belzer
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Publication number: 20110062392Abstract: The present disclosure provides various methods and systems for manufacture, transport and delivery of material including highly polarized nuclei that is in a hyperpolarized state.Type: ApplicationFiled: September 10, 2010Publication date: March 17, 2011Applicant: Millikelvin Technologies LLCInventors: Neal Kalechofsky, Avrum Belzer