Patents Assigned to Millikelvin Technologies LLC
  • Patent number: 10408895
    Abstract: A carrier for a sample of highly polarized material includes a shell having a radially exterior surface and a radially interior surface, and a sample of highly polarized material interiorly adjacent to the radially interior surface. The shell may be substantially cylindrical, and may be constructed from a magnetic or non-magnetic material. The sample of highly polarized material may comprise a methyl rotor group material. The sample of highly polarized material may comprise pyruvic acid or an acetic acid. The sample of highly polarized material may be co-axial with the cylindrical shell. The sample of highly polarized material may be bonded or frozen to the radially interior surface of the shell. The carrier may further comprise a wad of material that forms a volume and contacts an axially proximate end of at least one of the shell or the sample.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 10, 2019
    Assignees: Bruker Biospin Corporation, Millikelvin Technologies LLC
    Inventors: Matthew Hirsch, Avrum Belzer, Neal Kalechofsky, Charles Monroe
  • Patent number: 9714995
    Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses. In various illustrative methods, beneficial agents can be administered to samples or subjects to be studied. Some beneficial agents can include biomarkers, or precursors to biomarkers.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: July 25, 2017
    Assignee: Millikelvin Technologies LLC
    Inventor: Neil Kalechofsky
  • Patent number: 9606200
    Abstract: A method of providing a material sample in a state favorable to retaining spin polarization includes cooling a material sample from a temperature above a freezing point of the material sample down to a second temperature below the freezing point of the material sample; maintaining the sample at about the second temperature for a period of about several hours; and reducing temperature of the material sample to a third temperature lower than the second temperature to provide the material sample in a state favorable to retaining spin polarization, where the steps of cooling, maintaining and reducing are performed in the absence of an adulterant material. The method of providing a sample of pyruvic acid in a state favorable to retaining spin polarization may include cooling the sample of pyruvic acid in the absence of an adulterant material from a temperature above a freezing point of the sample of pyruvic acid down to less than about 200 Kelvin to provide the sample.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: March 28, 2017
    Assignees: Bruker Biospin Corporation, Millikelvin Technologies LLC
    Inventors: James G. Kempf, Neal Kalechofsky, Melanie Rosay
  • Patent number: 9014785
    Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: April 21, 2015
    Assignee: Millikelvin Technologies LLC
    Inventors: Neal Kalechofsky, Mirko Hrovat
  • Publication number: 20150061666
    Abstract: A method of providing a material sample in a state favorable to retaining spin polarization includes cooling a material sample from a temperature above a freezing point of the material sample down to a second temperature below the freezing point of the material sample; maintaining the sample at about the second temperature for a period of about several hours; and reducing temperature of the material sample to a third temperature lower than the second temperature to provide the material sample in a state favorable to retaining spin polarization, where the steps of cooling, maintaining and reducing are performed in the absence of an adulterant material. The method of providing a sample of pyruvic acid in a state favorable to retaining spin polarization may include cooling the sample of pyruvic acid in the absence of an adulterant material from a temperature above a freezing point of the sample of pyruvic acid down to less than about 200 Kelvin to provide the sample.
    Type: Application
    Filed: January 22, 2014
    Publication date: March 5, 2015
    Applicants: Millikelvin Technologies LLC, Bruker Biospin Corporation
    Inventors: James G. Kempf, Neal Kalechofsky, Melanie Rosay
  • Publication number: 20140285192
    Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 25, 2014
    Applicant: Millikelvin Technologies LLC
    Inventor: Neil Kalechofsky
  • Publication number: 20140285191
    Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 25, 2014
    Applicant: Millikelvin Technologies LLC
    Inventor: Neil Kalechofsky
  • Publication number: 20140266197
    Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Millikelvin Technologies LLC
    Inventor: Neil Kalechofsky
  • Publication number: 20140247047
    Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.
    Type: Application
    Filed: February 24, 2014
    Publication date: September 4, 2014
    Applicant: Millikelvin Technologies LLC
    Inventors: Neal Kalechofsky, Mirko Hrovat
  • Patent number: 8703102
    Abstract: The present disclosure provides various methods and systems for manufacture, transport and delivery of material including highly polarized nuclei that is in a hyperpolarized state.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: April 22, 2014
    Assignee: Millikelvin Technologies LLC
    Inventors: Neal Kalechofsky, Avrum Belzer
  • Patent number: 8703201
    Abstract: The disclosure provides various methods and systems for providing hyperpolarized materials as well as the hyperpolarized materials so provided. In addition, methods of providing hyperpolarized materials, such as agents, to end users from a remote location are also provided.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: April 22, 2014
    Assignee: Millikelvin Technologies LLC
    Inventors: Avrum Belzer, Neal Kalechofsky
  • Publication number: 20130154643
    Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.
    Type: Application
    Filed: February 11, 2013
    Publication date: June 20, 2013
    Applicant: Millikelvin Technologies LLC
    Inventor: Millikelvin Technologies LLC
  • Publication number: 20120114851
    Abstract: The disclosure provides various methods and systems for providing hyperpolarized materials as well as the hyperpolarized materials so provided. In addition, methods of providing hyperpolarized materials, such as agents, to end users from a remote location are also provided.
    Type: Application
    Filed: December 22, 2011
    Publication date: May 10, 2012
    Applicant: Millikelvin Technologies LLC
    Inventors: Neal Kalechofsky, Avrum Belzer
  • Publication number: 20110062392
    Abstract: The present disclosure provides various methods and systems for manufacture, transport and delivery of material including highly polarized nuclei that is in a hyperpolarized state.
    Type: Application
    Filed: September 10, 2010
    Publication date: March 17, 2011
    Applicant: Millikelvin Technologies LLC
    Inventors: Neal Kalechofsky, Avrum Belzer