Abstract: A method for performing remote tissue assessment of a tissue region includes selecting imaging parameters, obtaining M image datasets of the tissue region when the tissue region is illuminated by a light signal having a unique discrete wavelength, obtaining a reference image dataset of the tissue region without illumination, processing the M+1 image datasets to obtain M marker maps where each marker map corresponds to a different physiological marker, and analyzing at least one of the marker maps to determine whether a physiological condition exists at the tissue region or to monitor the status of an existing physiological condition at the tissue region. In one or more embodiments, the method may be performed by a portable light source unit including a housing configured for use with a mobile device having a camera, or by a system including a light source unit, an optical sensor module, and a mobile device.

Abstract: A method for positioning a portable multispectral imaging device within a target distance range relative to a surface for imaging a region of interest (ROI) of the surface. The method generally involves determining a distance between the portable multispectral imaging device and the ROI of the surface determining whether the distance is within the target distance range generating a signal indicating to a user that the portable multispectral imaging device is not within the target distance range and providing instructions to the user to guide that the user for repositioning the portable multispectral imaging device; and triggering an image capturing sequence when the portable multispectral imaging device is within the target distance range. A method for calibrating a light source unit of the portable multispectral imaging device and a portable multispectral imaging device are also described.