Patents Assigned to MINGSIGHT PHARMACEUTICALS, INC.
  • Treatment of cancer
    Patent number: 11154555
    Abstract: Provided herein are compositions and methods for the treatment of a hematological malignancy. Also disclosed herein are compositions and methods for the treatment of Ewings Sarcoma. Said compositions comprise isoform selective pyrrolo-pyrazole PKC inhibitors.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: October 26, 2021
    Assignee: MINGSIGHT PHARMACEUTICALS, INC.
    Inventors: Michael Niesman, Kai Zhang
  • PKC inhibitor solid state forms
    Patent number: 11104679
    Abstract: The present disclosure relates to various solid state forms of 5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-ylmethyl)piperazin-1-yl]carbonyl}-N-(5-fluoro-2-methylpyrimidin-4-yl)-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine and methods of making the same. Such forms of 5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-ylmethyl)piperazin-1-yl]carbonyl}-N-(5-fluoro-2-methylpyrimidin-4-yl)-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine are useful in preparation of pharmaceutical compositions and dosage forms for the treatment of cancer, immune disorders and inflammation.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: August 31, 2021
    Assignee: MINGSIGHT PHARMACEUTICALS, INC.
    Inventors: Kay Olmstead, Julian Northen
  • TREATMENT OF CANCER
    Publication number: 20190216809
    Abstract: Provided herein are compositions and methods for the treatment of a hematological malignancy. Also disclosed herein are compositions and methods for the treatment of Ewings Sarcoma. Said compositions comprise isoform selective pyrrolo-pyrazole PKC inhibitors.
    Type: Application
    Filed: July 13, 2017
    Publication date: July 18, 2019
    Applicant: MingSight Pharmaceuticals, Inc.
    Inventors: Michael NIESMAN, Kai ZHANG
  • Treatment of autoimmune disease
    Patent number: 9980965
    Abstract: Provided herein are compositions and methods for the treatment of autoimmune diseases, including lupus, uveitis and encephalitis. Said compositions useful for treating autoimmune diseases comprise pyrrolo-pyrazole PKC inhibitors.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: May 29, 2018
    Assignee: MINGSIGHT PHARMACEUTICALS, INC.
    Inventors: Michael Niesman, Kai Zhang
  • Treatment of autoimmune disease
    Patent number: 9814716
    Abstract: Provided herein are compositions and methods for the treatment of autoimmune diseases, including lupus, uveitis and encephalitis. Said compositions useful for treating autoimmune diseases comprise pyrrolo-pyrazole PKC inhibitors.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: November 14, 2017
    Assignee: MINGSIGHT PHARMACEUTICALS, INC.
    Inventors: Michael Niesman, Kai Zhang