Abstract: The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for use in the treatment of central nervous system (NS) disorders.
Type:
Application
Filed:
October 5, 2017
Publication date:
May 17, 2018
Applicant:
Minoryx Therapeutics S.L.
Inventors:
Ana Maria GARCÍA COLLAZO, David John Augustus Eckland, Maria Pilar Pizcueta Lalanza, Marc Martinell Pedemonte
Abstract: The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy) benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for use in the treatment of central nervous system (NS) disorders.
Type:
Grant
Filed:
May 5, 2016
Date of Patent:
October 10, 2017
Assignee:
MINORYX THERAPEUTICS S.L.
Inventors:
Ana María García Collazo, David John Augustus Eckland, Maria Pilar Pizcueta Lalanza, Marc Martinell Pedemonte
Abstract: The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy) benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for use in the treatment of central nervous system (NS) disorders.
Type:
Application
Filed:
May 5, 2016
Publication date:
August 18, 2016
Applicant:
MINORYX THERAPEUTICS S.L.
Inventors:
Ana Maria Garcia Collazo, David John Augustus Eckland, Maria Pilar Pizcueta Lalanza, Marc Martinell Pedemonte
Abstract: The present invention refers to compounds of formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of conditions associated with the alteration of the activity of ?-galactosidase, specially galactosidase beta-1 or GLB1, including GM1 gangliosidoses and Morquio syndrome, type B.
Type:
Application
Filed:
July 30, 2014
Publication date:
June 16, 2016
Applicant:
Minoryx Therapeutics S.L.
Inventors:
Xavier BARRIL ALONSO, Ana Maria GARCÍA COLLAZO, Juan AYMAMI BOFARULL, Marc REVÉS VILAPLANA, Rodolfo LAVILLA GRIFOLS, Marc MARTINELL PEDEMONTE