Patents Assigned to Miraculins, Inc.
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Patent number: 8712491Abstract: A process is provided for analyzing a skin in any of a number of biochemical or immunological tests for an analyte which involves applying to a skin surface on a patient a reagent which selectively binds to the analyte to form an analyte-reagent complex; subjecting the skin surface on the patient to a treatment which develops a color correlating to an amount of analyte in the specimen; measuring a hue angle of the color developed on the skin surface of the patient by measuring a reflectance over a range of visible light spectrum at a plurality of intervals in wavelength of the visible light spectrum to obtain a measurement; and correlating the measurement of the hue angle to determine a concentration of the analyte.Type: GrantFiled: July 5, 2012Date of Patent: April 29, 2014Assignee: Miraculins Inc.Inventor: Michael J. Evelegh
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Patent number: 8690792Abstract: Skin cholesterol is measured by applying an adhesive tape onto a selected area of the skin to adhere the tape to the selected skin area and stripping the tape off the selected skin area to obtain a sample representative of the outer stratum corneum layer of the skin, the sample adhering to the tape so as to have exposed skin constituents. The sample is assayed using a detector reagent that specifically binds to cholesterol and in addition has an indicator component that allows quantitation of the amount of cholesterol present in the exposed skin constituents.Type: GrantFiled: April 5, 2010Date of Patent: April 8, 2014Assignee: Miraculins Inc.Inventors: Peter Horsewood, Robert Zawydiwski
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Publication number: 20130323253Abstract: The present invention relates to the field of the diagnosis of large intestine/colon diseases. More particularly, the present invention provides a method for differential diagnosis of colorectal cancer from a non-malignant disease of the large intestine/colon, and from a healthy large intestine/colon. The invention also relates to treatment of colorectal cancer.Type: ApplicationFiled: June 1, 2011Publication date: December 5, 2013Applicant: MIRACULINS, INC.Inventors: Douglas Barker, Katrin Atnikov, Yilan Zhang, Stephen Frost
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Publication number: 20120277553Abstract: A process is provided for analyzing a specimen of biological material in any of a number of biochemical or immunological tests for an analyte which involves subjecting the specimen to treatment which develops a color correlating to the amount of analyte in the specimen. According to the invention at least one defined color characteristic selected from hue angle, chroma, saturation and lightness of the developed color is measured and the results of that measurement analyzed to determine the presence or concentration of the analyte in the specimen. Particular applications are to the detection of cancerous or pre-cancerous abnormalities from the analysis of lung mucus, throat mucus, cervical mucus or seminal fluid.Type: ApplicationFiled: July 5, 2012Publication date: November 1, 2012Applicant: MIRACULINS INC.Inventor: Michael J. Evelegh
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Patent number: 8236516Abstract: A process is provided for analyzing a specimen of biological material in any of a number of biochemical or immunological tests for an analyte which involves subjecting the specimen to treatment which develops a color correlating to the amount of analyte in the specimen. According to the invention at least one defined color characteristic selected from hue angle, chroma, saturation and lightness of the developed color is measured and the results of that measurement analyzed to determine the presence or concentration of the analyte in the specimen. Particular applications are to the detection of cancerous or pre-cancerous abnormalities from the analysis of lung mucus, throat mucus, cervical mucus or seminal fluid.Type: GrantFiled: July 9, 2004Date of Patent: August 7, 2012Assignee: Miraculins Inc.Inventor: Michael J. Evelegh
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Patent number: 8124367Abstract: The present invention provides a method and apparatus for non-invasive measurement of skin cholesterol. More particularly, one aspect of the invention provides for a device to apply a detector reagent to a selected area of skin. Another aspect of the invention provides for an indicator device to produce a visual change corresponding to the amount of detector reagent that is bound in the skin. The method and apparatus of this invention typically do not require any instrumentation for certain embodiments, allowing the invention to be suitable for self-testing, for example, but not limited to, in the home environment. As such the invention is particularly useful to allow individuals to assess their risk of atherosclerosis and related vascular diseases.Type: GrantFiled: February 28, 2006Date of Patent: February 28, 2012Assignee: Miraculins, Inc.Inventor: Peter Horsewood
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Publication number: 20120022793Abstract: The present invention includes the use of biomolecules for differential diagnosis of prostate cancer and/or non-malignant disease of the prostate. The present invention also provides methods for detecting biomolecules within a biological sample. The invention further includes kits for differential diagnosis of prostate cancer and/or non-malignant disease of the prostate in a biological sample.Type: ApplicationFiled: July 22, 2011Publication date: January 26, 2012Applicant: Miraculins, Inc.Inventors: Douglas BARKER, Katrin Atnikov, Yilan Zhang, Stephen Frost
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Publication number: 20120021925Abstract: The application refers to a method for diagnosing prostate cancer through the measurement of the combination of PSP94 (?-microseminoprotein) and F/T PSA biomarkers, the method using urine samples to measure PSP94 and serum samples to analyse F/T PSA. In one embodiment, the PSP94 is standardized to creatinine. Also based on the measurement of PSP94 and F/T PSA are provided methods and kits for (a) diagnosing aggressive prostate cancer; (b) differential diagnosis; and (c) diagnosing the progression of prostate cancer.Type: ApplicationFiled: January 19, 2010Publication date: January 26, 2012Applicant: MIRACULINS, INC.Inventors: Katrin Atnikov, Douglas Barker, Yilan Zhang, Stephen Frost
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Publication number: 20100216654Abstract: The present invention includes biomolecules and use of these biomolecules for differential diagnosis of prostate cancer and/or non-malignant disease of the prostate. In an embodiment, the present invention provides methods for detecting biomolecules within a biological sample as well as a database comprising of mass profiles of biomolecules specific for healthy subjects, subjects having a non-malignant disease of the prostate and subjects having prostate cancer. The invention further includes kits for differential diagnosis of prostate cancer and/or non-malignant disease of the prostate in a biological sample.Type: ApplicationFiled: March 12, 2008Publication date: August 26, 2010Applicant: MIRACULINS, INC.Inventors: Katrin Stedronsky, Douglas Barker, Yilan Zhang
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Publication number: 20080020940Abstract: The present invention relates to the field of the diagnosis of large intestine diseases. More particularly, embodiments of the invention provide a method for differential diagnosis of colorectal cancer from a non-malignant disease of the large intestine, and from a healthy large intestine.Type: ApplicationFiled: July 24, 2007Publication date: January 24, 2008Applicant: Miraculins Inc.Inventors: Katrin Stedronsky, Douglas Barker, Yilan Zhang