Abstract: An endoscopic suturing device comprising an elongate hollow tube, one end of which carries a thread engaging and loop forming member and a thread or needle jaw member. An actuating member at the other end of the tube engages an elongate actuating rod extending through the tube and is coupled to the thread or needle jaw member, whereby axial movement of the actuating member against the biasing action of a spring causes the actuating rod to actuate the thread or needle clamping member. The device is capable of disassembly for easy cleaning and sterilization.