Abstract: The present invention relates to methods of detecting preliminary stages of testicular germ cell tumors, more particularly testicular intraepithelial neoplasia (TIN), in a subject and to the use of miR-371a-3p as a biomarker for the detection of TIN. It further relates to the use of miR-371a-3p-specific primers and/or miR-371a-3p-specific probes and of corresponding kits for the detection of TIN.
Type:
Grant
Filed:
November 2, 2017
Date of Patent:
May 9, 2023
Assignee:
miRdetect GmbH
Inventors:
Meike Spiekermann, Nina Winter, Gazanfer Belge, Arlo Radtke