Abstract: A computer specific system for receiving a plurality of medical imaging specific 3D patient specific data sets from different 3D data sources, for a patient receiving reconstructive surgery, locating and applying a plurality of landmarks to each data set, and performing an overlay analysis procedure that aligns the 3D data sets from the different 3D data sources to create a 3D medical image representation of the patient's tissue. The 3D representation can be used to create 3D models for use by surgeons to perform reconstructive surgical procedures.