Abstract: The present invention provides novel mitochondrial fusion transcripts, the parent mutated mtDNA molecules, and the resulting translation products (proteins) for predicting, diagnosing and/or monitoring cancer. Hybridization probes complementary thereto for use in the methods of the invention are also provided.
Type:
Grant
Filed:
March 29, 2010
Date of Patent:
May 6, 2014
Assignee:
Mitomics Inc.
Inventors:
Ryan Parr, Gabriel Dakubo, Andrew Harbottle, Brian Reguly, Jennifer Creed, Kerry Robinson, Daniel Klein
Abstract: Mitochondrial DNA deletions useful for the detection of cancers and sun exposure are provided. In particular, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melanoma skin cancer are provided.
Type:
Grant
Filed:
October 18, 2007
Date of Patent:
August 30, 2011
Assignee:
Mitomics Inc.
Inventors:
Ryan Parr, Robert Thayer, Gabriel Dakubo, Jennifer Maki, Kerry Robinson, Andrea Maggrah, Brian Reguly, Andrew Harbottle, Mark Birch-Machin