Patents Assigned to Mitos Pharmaceuticals, Inc.
  • Nitroxides for use in treating or preventing diabetes and obesity
    Patent number: 10245256
    Abstract: Pharmaceutical compositions are provided that are useful in treating diabetes. The compositions comprise a pharmaceutically acceptable carrier, and an effective therapeutic or prophylactic amount of a nitroxide antioxidant that alters the expression of genes related to diabetes. Methods are also provided for the use of the pharmaceutical compositions in the treatment or prevention of diabetes. In a preferred embodiment, the nitroxide antioxidant is Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl).
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: April 2, 2019
    Assignee: Mitos Pharmaceuticals, Inc.
    Inventors: Louis Habash, Clarence Jones
  • Nitroxides for use in treating or preventing diabetes and obesity
    Patent number: 9522143
    Abstract: Pharmaceutical compositions are provided that are useful in treating diabetes. The compositions comprise a pharmaceutically acceptable carrier, and an effective therapeutic or prophylactic amount of a nitroxide antioxidant that alters the expression of genes related to diabetes. Methods are also provided for the use of the pharmaceutical compositions in the treatment or prevention of diabetes. In a preferred embodiment, the nitroxide antioxidant is Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl).
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: December 20, 2016
    Assignee: Mitos Pharmaceuticals, Inc.
    Inventors: Louis Habash, Clarence Jones
  • Nitroxides for use in treating or preventing diabetes and obesity
    Patent number: 9522144
    Abstract: Pharmaceutical compositions are provided that are useful in treating diabetes. The compositions comprise a pharmaceutically acceptable carrier, and an effective therapeutic or prophylactic amount of a nitroxide antioxidant that alters the expression of genes related to diabetes. Methods are also provided for the use of the pharmaceutical compositions in the treatment or prevention of diabetes. In a preferred embodiment, the nitroxide antioxidant is Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl).
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: December 20, 2016
    Assignee: Mitos Pharmaceuticals, Inc.
    Inventors: Louis Habash, Clarence Jones
  • Nitroxides for use in treating or preventing diabetes and obesity
    Patent number: 9101619
    Abstract: Pharmaceutical compositions are provided that are useful in treating diabetes. The compositions comprise a pharmaceutically acceptable carrier, and an effective therapeutic or prophylactic amount of a nitroxide antioxidant that alters the expression of genes related to diabetes. Methods are also provided for the use of the pharmaceutical compositions in the treatment or prevention of diabetes. In a preferred embodiment, the nitroxide antioxidant is Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl).
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: August 11, 2015
    Assignee: Mitos Pharmaceuticals, Inc.
    Inventors: Louis Habash, Clarence Jones
  • NITROXIDES FOR USE IN TREATING OR PREVENTING DIABETES AND OBESITY
    Publication number: 20140045891
    Abstract: Pharmaceutical compositions are provided that are useful in treating diabetes. The compositions comprise a pharmaceutically acceptable carrier, and an effective therapeutic or prophylactic amount of a nitroxide antioxidant that alters the expression of genes related to diabetes. Methods are also provided for the use of the pharmaceutical compositions in the treatment or prevention of diabetes. In a preferred embodiment, the nitroxide antioxidant is Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl).
    Type: Application
    Filed: October 18, 2013
    Publication date: February 13, 2014
    Applicant: Mitos Pharmaceuticals, Inc.
    Inventors: Louis Habash, Clarence Jones
  • Nitroxides for use in treating predisposed or at risk patients
    Patent number: 8563581
    Abstract: Pharmaceutical compositions are provided that are useful in treating diabetes. The compositions comprise a pharmaceutically acceptable carrier, and an effective therapeutic or prophylactic amount of a nitroxide antioxidant that alters the expression of genes related to diabetes. Methods are also provided for the use of the pharmaceutical compositions in the treatment or prevention of diabetes. In a preferred embodiment, the nitroxide antioxidant is Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl).
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: October 22, 2013
    Assignee: Mitos Pharmaceuticals, Inc.
    Inventors: Louis Habash, Clarence Jones
  • METHODS OF USING NITROXIDES IN CONJUNCTION WITH PHOTOSENSITIZERS AND SONOSENSITIZERS
    Publication number: 20100241197
    Abstract: The teachings herein relate to new methods of ameliorating the negative effects of a photosensitizer or sonosensitizer in a patient using a nitroxide.
    Type: Application
    Filed: June 4, 2010
    Publication date: September 23, 2010
    Applicant: Mitos Pharmaceuticals, Inc.
    Inventors: Kenneth Chang, Louis Habash
  • PROPHYLACTIC PRETREATMENT WITH ANTIOXIDANTS
    Publication number: 20100240700
    Abstract: Methods, compositions, and uses for pre-treating patients who are susceptible to ischemia, including stroke, with nitroxides, in order to prevent or ameliorate the effects of stroke or other ischemic disease.
    Type: Application
    Filed: June 3, 2010
    Publication date: September 23, 2010
    Applicant: MITOS PHARMACEUTICALS, INC.
    Inventor: Kameron W. Maxwell
  • Nitroxide radioprotector formulations and methods of use
    Patent number: 7625928
    Abstract: Pharmaceutical compositions useful in preventing and treating negative side effects accompanying radiotherapy are disclosed. More particularly, new formulations that can be applied to the skin and mucous membranes of patients undergoing radiotherapy and methods of using these formulations are disclosed.
    Type: Grant
    Filed: September 29, 2003
    Date of Patent: December 1, 2009
    Assignee: Mitos Pharmaceuticals, Inc.
    Inventors: Kameron W. Maxwell, Peter C. Hoyle
  • NITROXIDE RADIOPROTECTOR FORMULATIONS AND METHODS OF USE
    Publication number: 20090247580
    Abstract: Pharmaceutical compositions useful in preventing and treating negative side effects accompanying radiotherapy are disclosed. More particularly, new formulations that can be applied to the skin and mucous membranes of patients undergoing radiotherapy and methods of using these formulations are disclosed.
    Type: Application
    Filed: June 5, 2009
    Publication date: October 1, 2009
    Applicant: Mitos Pharmaceuticals, Inc.
    Inventors: Kameron W. Maxwell, Peter C. Hoyle
  • Prophylactic pretreatment with antioxidants
    Publication number: 20070123567
    Abstract: Methods, compositions, and uses for pre-treating patients who are susceptible to ischemia, including stroke, with nitroxides, in order to prevent or ameliorate the effects of stroke or other ischemic disease.
    Type: Application
    Filed: April 22, 2004
    Publication date: May 31, 2007
    Applicant: Mitos Pharmaceuticals Inc.
    Inventor: Kameron Maxwell