Patents Assigned to Mitsui Pharmaceuticals, Inc.
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Patent number: 5976523Abstract: The present invention provides a method for the screening of a wound-healing agent, which comprises determining a substance to be active as a wound-healing agent on the basis of potentiation or modification of biological activities of a growth and/or differentiation factor, a growth hormone or a cytokine. This invention also provides a wound-healing method, which comprises as an active ingredient a compound of the following formula (1) or formula (2) found to be active by the screening method.Type: GrantFiled: May 16, 1996Date of Patent: November 2, 1999Assignee: Mitsui Pharmaceuticals, Inc.Inventors: Akira Awaya, Fumiaki Ito, Kojun Torigoe, Ikuo Tomino
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Patent number: 5582795Abstract: A hold-transfer system for extraction containers has a main body and a cassette detachable from the main body. The cassette has holding devices for holding extraction containers in an upright position, an endless traveling member carrying the holding devices arranged in a row, and a driving rotor and a driven rotor engaging the endless traveling member about perimeters thereof. The endless traveling member has rotatable support member for rotatably supporting the holding devices with lower portions of the holding devices protruding below the rotatable support members and accessible from beneath the cassette. The main body has a driving motor for driving the driving rotor and an identifying device, installed at a reading position relative to a specified position for an extraction, for identifying an identification mark associated with one of the extraction containers.Type: GrantFiled: April 5, 1995Date of Patent: December 10, 1996Assignees: Furuno Electric Company, Limited, Mitsui Pharmaceuticals, Inc.Inventors: Takashi Nishina, Ryoichi Ito
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Patent number: 5464816Abstract: A pharmaceutical composition containing serum thymic factor (FTS) and a method for using FTS containing compositions for treating a variety of immunodeficiencies and autoimmune diseases including multiple sclerosis, Guillain-Barre syndrome, inflammatory neuropathy, polyneuritis and other immunodemyelinating diseases.Type: GrantFiled: March 26, 1990Date of Patent: November 7, 1995Assignee: Mitsui Pharmaceuticals Inc.Inventors: Yoshitaka Nagai, Hayao Abe, Masanobu Arita
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Patent number: 5358945Abstract: The present invention relates to pyrimidine compounds represented by the formula ##STR1## (wherein X is a substituted or a cyclic amino group and Y is a substituted amino group or a substituted carbonyl group) or their pharmaceutically acceptable salts, and a therapeutic agent for neurological diseases comprising the compounds.These compounds are useful for treatment of various disorders in nervous systems since they are effective on growth of neurons and promotion of the formation and elongation of neutrites.Type: GrantFiled: March 30, 1992Date of Patent: October 25, 1994Assignees: Mitsui Petrochemical Industries, Ltd., Mitsui Pharmaceuticals, Inc.Inventors: Akira Mizuchi, Ken Ikeda, Yuichiro Kokubun, Kazutoshi Horikomi, Tadayuki Sasaki, Akira Awaya, Ikuo Tomino, Masaharu Ishiguro, Takumi Kitahara, Noriaki Kihara
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Patent number: 5304555Abstract: This invention provides novel pyrimidines or their pharmaceutically acceptable salts thereof and process for preparation thereof. The novel compounds are useful for neurological diseases of the peripheral and central nervous systems of animals.Type: GrantFiled: October 19, 1990Date of Patent: April 19, 1994Assignees: Mitsui Petrochemical Industries, Ltd., Mitsui Pharmaceuticals, Inc.Inventors: Akira Awaya, Kazutoshi Horikomi, Tadayuki Sasaki, Hisashi Kobayashi, Akira Mizuchi, Takuo Nakano, Ikuo Tomino, Shintaro Araki, Mitsuyuki Takesue, Koji Kato, Keiichi Yokoyama
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Patent number: 5183638Abstract: An immunity analysis apparatus for use with magnetic particles in which a sample is transferred to a reaction vessel and the reaction vessel is conveyed past several devices for adding and agitating a magnetic particle solution, adding a stroma solution, absorbing the particles to an inner wall of the reaction vessels to remove the reaction solution, adding an enzyme labelling antibody solution, absorbing the particle on an inner wall a second time to remove the resulting solution, adding a stop solution, measuring the result, and cleaning the reaction vessels for a reuse. The device additionally has structure for agitating the magnetic particle reagent solution containers and moving a pipet arm independent of an L-shaped agitating rod arm during a portion of its movement to supply the reaction vessels with the magnetic particle solution.Type: GrantFiled: December 3, 1990Date of Patent: February 2, 1993Assignees: Kabushiki Kaisha Nittec, Mitsui Pharmaceuticals, Inc.Inventor: Koichi Wakatake
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Patent number: 5112810Abstract: A pharmaceutical composition containing serum thymic factor (FTS) and a method for using FTS containing compositions for treating a variety of immunodeficiencies and autoimmune diseases including multiple sclerosis, Guillain-Barre syndrome, inflammatory neuropathy, polyneuritis and other immunodemyelinating diseases.Type: GrantFiled: May 15, 1985Date of Patent: May 12, 1992Assignee: Mitsui Pharmaceuticals, Inc.Inventors: Yoshitaka Nagai, Hayao Abe, Masanobu Arita
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Patent number: 4959368Abstract: A pharmaceutical composition comprising a pyrimidine represented by the following formula ##STR1## wherein R.sup.1 represents a hydrogen atom, an acyl group having 2 to 4 carbon atoms, an alkoxycarbonyl group having 2 to 5 carbon atoms, an alkoxycarbonylmethyl group having 3 to 5 carbon atoms, a 3,4-dimethoxybenzoyl group or a 3,4-methylenedioxybenzyl group,R.sup.2 represents a hydrogen atom, an amino group, a monoalkylamino group having 1 to 4 carbon atoms, an alkoxy group having 1 to 5 carbon atoms or an alkoxycarbonyl group having 2 to 4 carbon atoms,R.sup.3 represents a hydrogen atom, an alkoxycarbonyl group having 2 to 4 carbon atoms, a dialkylaminocarbonyl group having 1 to 9 carbon atoms in each alkyl moiety, an alkoxy group having 1 to 5 carbon atoms, or a hydroxyethyl group, R.sup.2 and R.sup.3, together with the carbon atoms to which they are bonded, may form a 5- to 7-membered carbocyclic ring or a heterocyclic ring having N, O or S as the hetero atom, and R.sup.Type: GrantFiled: October 22, 1987Date of Patent: September 25, 1990Assignees: Mitsui Petrochemical Industries Ltd., Mitsui Pharmaceuticals, Inc.Inventors: Akira Awaya, Takuo Nakano, Hisashi Kobayashi, Ken E. Tan, Kazutoshi Horikomi, Tadayuki Sasaki, Keiichi Yokoyama, Hiroyasu Ohno, Kozi Kato, Takumi Kitahara, Ikuo Tomino, Shigeru Isayama