Patents Assigned to MIZ COMPANY LIMITED
  • Publication number: 20240009419
    Abstract: There are provided a gas supply apparatus and a gas supply method that are capable of supplying hydrogen gas of a highly accurate and stable hydrogen gas concentration to a body. A ventilator 100 that supplies oxygen-containing gas and hydrogen gas includes a hydrogen gas delivery unit 8 that delivers the hydrogen gas taken in to outside of the ventilator 100, and a control unit 22 that adjusts an amount of the hydrogen gas taken into the hydrogen gas delivery unit 8. The control unit 22 adjusts the amount of the hydrogen gas taken into the hydrogen gas delivery unit 8 based on a flow rate of the oxygen-containing gas.
    Type: Application
    Filed: August 14, 2023
    Publication date: January 11, 2024
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Bunpei SATO, Yusuke ICHIKAWA
  • Publication number: 20230310496
    Abstract: Provided is a composition for improving symptoms of organ-specific autoimmune diseases. A composition comprising a hydrogen gas-containing gas as an active ingredient, for use in improving symptoms caused by an organ-specific autoimmune disease and/or reducing worsening of the symptoms in patients with an organ-specific autoimmune disease, and a method for improving symptoms including a decrease in activity levels involved in symptoms of an organ-specific autoimmune disease and/or reducing worsening of the symptoms by administering the composition to patients with the organ-specific autoimmune disease.
    Type: Application
    Filed: March 17, 2023
    Publication date: October 5, 2023
    Applicant: MiZ Company Limited
    Inventors: Yusuke ICHIKAWA, Fumitake SATOH, Bunpei SATO, Yasuko GINJYO
  • Publication number: 20230256007
    Abstract: Provided is a novel composition that has no side effects and can be easily produced, for use in improving symptoms of sequelae of viral infection. A composition comprising a hydrogen gas-containing gas as an active ingredient, for use in improving symptoms of sequelae of viral infection, such as pulmonary fibrosis, feeling of fatigue, malaise, shortness of breath, difficulty breathing, and/or decrease in activity levels associated with these symptoms, in a patient with sequelae of viral infection, and/or a method for improving symptoms, such as decrease in activity levels associated with these symptoms.
    Type: Application
    Filed: January 23, 2023
    Publication date: August 17, 2023
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Yoshiyasu TAKEFUJI, Takashi YAMAMURA, Bunpei SATO, Shinichi HIRANO, Yusuke ICHIKAWA
  • Publication number: 20230158267
    Abstract: Described is a composition for ameliorating symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and/or fibromyalgia (FM) that has few side effects and can be easily produced. Specifically, described is a composition for ameliorating at least one symptom of fatigue, headache, body pain, impaired thinking, impaired concentration, and/or impaired activity level associated with these symptoms caused by ME/CFS and/or FM in a patient, including a hydrogen gas-containing gas as an active ingredient. Also, described herein is a method for ameliorating symptoms such as fatigue, headache, body pain, impaired thinking, impaired concentration, and/or impaired activity levels associated with these symptoms caused by ME/CFS and/or FM in a patient with ME/CFS and/or FM, including administering the composition to the patient.
    Type: Application
    Filed: September 8, 2022
    Publication date: May 25, 2023
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Yoshiyasu TAKEFUJI, Takashi YAMAMURA, Bunpei SATO, Shin-ichi HIRANO, Yusuke ICHIAKWA
  • Patent number: 11529367
    Abstract: The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: December 20, 2022
    Assignees: MIZ COMPANY LIMITED, INCORPORATED MEDICAL INSTITUTION YUKOKAI
    Inventors: Yukimasa Aoki, Shinichi Hirano, Bunpei Sato, Ryosuke Kurokawa
  • Publication number: 20220023335
    Abstract: The present invention provides a composition for prevention and/or improvement of an adverse drug reaction, a symptom associated with an adverse drug reaction, and/or an adverse reaction associated with medical treatment. More specifically, the present invention provides a composition for prevention and/or improvement of an adverse drug reaction, a symptom associated with an adverse drug reaction, and/or an adverse reaction associated with medical treatment in a subject, comprising molecular hydrogen as an active ingredient.
    Type: Application
    Filed: July 15, 2021
    Publication date: January 27, 2022
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Bunpei SATO, Yusuke ICHIKAWA, Shinichi HIRANO, Yoshihiro MITEKURA
  • Patent number: 11147834
    Abstract: The present application provides a composition for treatment or prophylaxis of age-related macular degeneration in a subject, comprising molecular hydrogen as an active ingredient, and a method for treatment or prophylaxis of age-related macular degeneration, comprising administering the composition to a subject with age-related macular degeneration.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: October 19, 2021
    Assignee: MIZ COMPANY LIMITED
    Inventors: Fumitake Satoh, Shinichi Hirano, Yusuke Ichikawa, Takeshirou Takekoshi
  • Publication number: 20210299162
    Abstract: The present invention provides a composition for prevention and/or improvement of encephalitis and/or meningitis. More specifically, the present invention provides a composition for prevention and/or improvement of encephalitis and/or meningitis and a symptom associated with the encephalitis and/or meningitis in a subject, comprising molecular hydrogen as an active ingredient.
    Type: Application
    Filed: March 19, 2021
    Publication date: September 30, 2021
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Bunpei SATO, Yusuke ICHIKAWA, Shinichi HIRANO, Ryosuke KUROKAWA
  • Publication number: 20210275577
    Abstract: The present invention provides a composition for regulating intracellular signal transduction. More specifically, the present invention provides a composition for prevention and/or improvement of a symptom associated with intracellular signal transduction in a subject, comprising molecular hydrogen as an active ingredient.
    Type: Application
    Filed: March 3, 2021
    Publication date: September 9, 2021
    Applicants: MiZ Company Limited, Osaka University
    Inventors: Fumitake SATOH, Bunpei SATO, Shinichi HIRANO, Ryosuke KUROKAWA, Yusuke ICHIKAWA, Hiroshi MATSUURA, Kentaro SHIMIZU, Hiroshi OGURA, Takeshi SHIMAZU
  • Publication number: 20210275575
    Abstract: The present application provides a composition for improving or preventing human renal diseases, containing molecular hydrogen as an active ingredient, for example, a composition for improving or preventing renal diseases in a human patient having acute or chronic nephritis, renal failure, and/or nephrotic syndrome, for example, for improving urinary protein and urinary protein/urinary creatinine ratio to a normal range, and a method for improving renal diseases by administering the composition to the patient.
    Type: Application
    Filed: March 1, 2021
    Publication date: September 9, 2021
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Ryosuke KUROKAWA, Hideyuki SASAKI, Yoshiaki SASAKI
  • Publication number: 20210275576
    Abstract: The present invention provides a composition for prevention and/or improvement of a genetic disorder. More specifically, the present invention provides a composition for prevention and/or improvement of a genetic disorder and a symptom associated with the genetic disorder in a subject, comprising molecular hydrogen as an active ingredient.
    Type: Application
    Filed: March 2, 2021
    Publication date: September 9, 2021
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Bunpei SATO, Yusuke ICHIKAWA, Shinichi HIRANO, Ryosuke KUROKAWA
  • Publication number: 20210268017
    Abstract: The present invention provides a composition for prevention and/or improvement of pneumonia. More specifically, the present invention provides a composition for prevention and/or improvement of pneumonia and a symptom associated with pneumonia in a subject, comprising molecular hydrogen as an active ingredient.
    Type: Application
    Filed: February 25, 2021
    Publication date: September 2, 2021
    Applicant: MiZ Company Limited
    Inventors: Fumitake SATOH, Bunpei Sato, Yusuke Ichikawa, Shinichi Hirano, Ryosuke Kurokawa
  • Patent number: 11033574
    Abstract: A method for treating schizophrenia, comprising administering a composition containing a therapeutically effective amount of hydrogen gas to a subject in need of the treatment, by inhalation, is provided by the present invention.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: June 15, 2021
    Assignee: MIZ COMPANY LIMITED
    Inventors: Fumitake Sato, Masatsugu Saito, Ryosuke Kurokawa
  • Patent number: 11026967
    Abstract: This application provides a composition comprising hydrogen gas or dissolved hydrogen as an active ingredient for suppressing or preventing abnormality in the intestinal environment of a subject, wherein the abnormality is selected from the group consisting of bacterial translocation and bacterial species composition abnormality of intestinal flora.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: June 8, 2021
    Assignees: MIZ COMPANY LIMITED, OSAKA UNIVERSITY
    Inventors: Mitsunori Ikeda, Kentaro Shimizu, Hiroshi Ogura, Shinichi Hirano, Ryosuke Kurokawa
  • Patent number: 10435798
    Abstract: A hydrogen gas generator comprises: an electrolyzer (2) configured to include a housing (20), a first chamber (21), a second chamber (22), a membrane (25), and a pair of electrode plates (23, 24); a tank (6) configured to store water to be electrolyzed (W); an electric power source (3) configured to apply a DC voltage to the pair of electrode plates; a diluter (4) configured to introduce a diluent gas into the first chamber or the second chamber in which the electrode plate to be a cathode is provided, the diluent gas diluting hydrogen gas generated; an electric quantity detector (51) configured to detect an electric quantity given to the electrode plate to be the cathode; a flow rate detector (52) configured to detect a flow rate of the diluent gas from the diluter; a calculator (5) configured to calculate a concentration of the diluted hydrogen gas on the basis of the electric quantity detected by the electric quantity detector and the flow rate detected by the flow rate detector; and an indicator (54) conf
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: October 8, 2019
    Assignee: MIZ Company Limited
    Inventors: Ryousuke Kurokawa, Kenji Tanaka, Fumitake Satoh, Bunpei Satoh
  • Patent number: 9636358
    Abstract: A device for producing a hydrogen containing fluid, having a container that stores fluid which able to be used for a living organism and has water vapor permeability, a hydrogen generating system that generates hydrogen by using moisture, and a wrapping member that encloses the container and the hydrogen generating system and has low hydrogen molecule permeability. The wrapping member encloses the container and the hydrogen generating system located outside the container, and a treatment to increase humidity in a space between an outer surface of the container and an inner surface of the wrapping member is performed.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: May 2, 2017
    Assignee: MIZ COMPANY LIMITED
    Inventors: Fumitake Satoh, Ryousuke Kurokawa, Bunpei Satoh