Patents Assigned to MJ Bioworks Incorporated
  • Polymorphism and haplotype scoring by differential amplification of polymorphisms
    Publication number: 20060051749
    Abstract: The current invention provides a method of performing DNA polymorphism assays. The assay combines allele-specific PCR with technology used for quantitative PCR. The method can be used to score the presence of absence of particular polymorphisms in a DNA sample. In a further aspect of the invention, the method is used to score the presence or absence of particular haplotypes in a DNA sample.
    Type: Application
    Filed: November 27, 2002
    Publication date: March 9, 2006
    Applicant: MJ BIOWORKS INCORPORATED
    Inventors: Yan Wang, Lei Xi, Michael Finney, Fan Chen
  • Novel compositions with polymerase activity
    Publication number: 20040219558
    Abstract: The invention provides novel compositions with polymerase activity and methods of using the compositions.
    Type: Application
    Filed: July 25, 2003
    Publication date: November 4, 2004
    Applicant: MJ Bioworks Incorporated
    Inventors: Peter B. Vander Horn, Yan Wang
  • Sso7-polymerase conjugate proteins
    Publication number: 20040081963
    Abstract: This invention provides Sso7-polymerase conjugates that exhibit improved activity in a polymerase reaction.
    Type: Application
    Filed: October 23, 2002
    Publication date: April 29, 2004
    Applicant: MJ Bioworks Incorporated
    Inventor: Yan Wang
  • Methods of using improved polymerases
    Publication number: 20040002076
    Abstract: This invention provides for methods of sequencing and performing polymerase reactions using an improved generation of nucleic acid polymerases. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the processivity of the polymerase.
    Type: Application
    Filed: November 27, 2002
    Publication date: January 1, 2004
    Applicant: MJ Bioworks Incorporated
    Inventors: Yan Wang, Peter Vander Horn, Lei Xi
  • Nucleic acid modifying enzymes
    Publication number: 20030162173
    Abstract: This invention provides for an improved generation of novel nucleic acid modifying enzymes. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the ability of the enzyme to bind and catalytically modify the nucleic acid.
    Type: Application
    Filed: May 30, 2001
    Publication date: August 28, 2003
    Applicant: MJ Bioworks Incorporated
    Inventors: Yan Wang, Lei Xi, Dennis E. Prosen
  • Parallel polymorphism scoring by amplification and error correction
    Publication number: 20030138830
    Abstract: This invention provides a method of detecting polymorphisms, e.g., single nucleotide polymorphisms (SNPs), by amplification and error correction. The invention encompasses methods of performing amplification and error correction using an improved generation of nucleic acid polymerases, and methods of multiplexing the assay. The improvement to the polymerases is the joining of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the ability of the enzyme to bind and catalytically modify the nucleic acid.
    Type: Application
    Filed: November 27, 2002
    Publication date: July 24, 2003
    Applicant: MJ Bioworks Incorporated
    Inventors: Yan Wang, Michael Finney, Fan Chen