Patents Assigned to MMV MEDICINES FOR MALARIA VENTURE
  • Patent number: 10011616
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: July 3, 2018
    Assignee: MMV MEDICINES FOR MALARIA VENTURE
    Inventors: Yong-Kang Zhang, Jacob J. Plattner, Robert T. Jacobs
  • Patent number: 9957253
    Abstract: The present invention relates to triaminopyrimidines and to pharmaceutically acceptable salts thereof, to their use in the treatment and/or prevention of malaria caused by plasmodium species, and to their methods of preparation.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: May 1, 2018
    Assignee: MMV MEDICINES FOR MALARIA VENTURE
    Inventors: Shahul Hameed Peer Mohamed, Vikas Patil, Kannan Murugan, Eknath Vithalrao Bellale, Anandkumar Raichurkar, Sudhir Landge, Jayashree Puttur, Nilanjana Roy Choudhury, Gajanan Shanbhag, Krishna Koushik, Pravin Iyer, Vasan Kirthika Sambandamurthy, Suresh Solapure, Shridhar Narayanan
  • Patent number: 9464057
    Abstract: The present invention is related to a use of pyrazole derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to pyrazole derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: October 11, 2016
    Assignees: MMV MEDICINES FOR MALARIA VENTURE, DREXEL UNIVERSITY, UNIVERSITY OF WASHINGTON
    Inventors: Jeremy Burrows, Matthew Wyvratt, Akhil Vaidya, Sandhya Kortagere, Erkang Fan, Arnab Kumar Chatterjee, Advait Suresh Nagle, Tomoyo Kato
  • Patent number: 9416124
    Abstract: In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl -1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: August 16, 2016
    Assignees: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MMV MEDICINES FOR MALARIA VENTURE, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Rodney Kiplin Guy, Fangyi Zhu, Wendyam Armand Guiguemde, David Floyd, Spencer Knapp, Philip Stein, Steve Castro
  • Patent number: 9266842
    Abstract: The present invention is related to a use of aminopyrazine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyrazine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: February 23, 2016
    Assignees: MMV MEDICINES FOR MALARIA VENTURE, UNIVERSITY OF CAPE TOWN
    Inventors: Yassir Younis, Kelly Chibale, Michael John Witty, David Waterson
  • Patent number: 9238653
    Abstract: Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: January 19, 2016
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, MMV MEDICINES FOR MALARIA VENTURE, UNIVERSITY OF WASHINGTON
    Inventors: Pradipsinh K. Rathod, David Floyd, Jeremy Burrows, Alka Marwaha, Ramesh Gujjar, Jose Coteron-Lopez, Margaret Phillips, Susan A. Charman, David Matthews
  • Patent number: 9024033
    Abstract: The present invention is related to a use of aminopyridine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyridine derivatives useful for the preparation of a pharmaceutical foimulation for the inhibition of malaria parasite proliferation.
    Type: Grant
    Filed: January 17, 2011
    Date of Patent: May 5, 2015
    Assignee: MMV Medicines for Malaria Venture
    Inventors: Michael John Witty, David Hardick
  • Publication number: 20140235593
    Abstract: In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl-1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: August 24, 2012
    Publication date: August 21, 2014
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, MMV MEDICINES FOR MALARIA VENTURE
    Inventors: Rodney Kiplin Guy, Fangyi Zhu, Wendyam Armand Guiguemde, David Floyd, Spencer Knapp, Philip Stein, Steve Castro
  • Publication number: 20120295905
    Abstract: The present invention is related to a use of aminopyridine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyridine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation.
    Type: Application
    Filed: January 17, 2011
    Publication date: November 22, 2012
    Applicant: MMV MEDICINES FOR MALARIA VENTURE
    Inventors: Michael John Witty, David Hardick