Abstract: The present invention relates to compounds represented by general formula (Ia), (Ib), (IIa) or (IIb). These compounds are suitable for imaging alpha-synuclein and for diagnosing diseases which are associated with the aggregation of alpha-synuclein. The compounds are also useful for treating and preventing diseases which are associated with the aggregation of alpha-synuclein.
Type:
Application
Filed:
November 19, 2020
Publication date:
March 2, 2023
Applicants:
MODAG GMBH, MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
Inventors:
Armin GIESE, Felix SCHMIDT, Daniel WECKBECKER, Andrei LEONOV, Sergey RYAZANOV, Christian GRIESINGER, Bernd PICHLER, Kristina HERFERT, Andreas MAURER, Laura KÜBLER, Sabrina BUSS