Abstract: The present invention relates to a process for preparing pharmaceutical compositions and other herbal products derived from herbs of Traditional Chinese Medicine (TCM), including Radix astragali (Milkvetch—Huang Qi), Ligusticum chuanxiong (Chuan Xiong), Radix angelicae sinensis (Chinese Angelica—Dang Gui) and Radix polygalae (Thinleaf milkwort—Yuan Zhi). The process includes a single extraction of the TCM herbs by heating in a hydro-alcoholic solvent, wherein the alcohol may be ethanol. FIG. 2 provides an overview of one embodiment of the process. The invention also relates to products of the process of the invention, and their use in the treatment of stroke and various neurological disorders.
Abstract: There is disclosed the use of a composition for promoting neuronal growth of neurons in tissues of the central or peripheral nervous system. There is also disclosed a method for inducing proliferation or differentiation of neuronal cells.
Type:
Grant
Filed:
February 8, 2016
Date of Patent:
January 29, 2019
Assignee:
MOLEAC PTE. LTD.
Inventors:
Michel Maurice Jacques Lazdunski, Catherine Louise Heurteaux, David Picard
Abstract: The present invention provides compositions and methods for treating stroke patients using TCM and a Western medicament used for the treatment of stroke patients.
Type:
Grant
Filed:
September 3, 2014
Date of Patent:
July 19, 2016
Assignee:
MOLEAC PTE. LTD.
Inventors:
David Picard, Xue Min Shi, Michael Lazdunski
Abstract: There is disclosed the use of a composition for promoting neuronal growth of neurons in tissues of the central or peripheral nervous system. There is also disclosed a method for inducing proliferation or differentiation of neuronal cells.
Type:
Grant
Filed:
March 29, 2010
Date of Patent:
March 22, 2016
Assignee:
MOLEAC PTE. LTD.
Inventors:
Michel Maurice Jacques Lazdunski, Catherine Louise Heurteaux, David Picard
Abstract: The present invention provides compositions and methods for treating stroke patients using TCM and a Western medicament used for the treatment of stroke patients.
Type:
Grant
Filed:
November 10, 2009
Date of Patent:
October 7, 2014
Assignee:
Moleac Pte. Ltd.
Inventors:
David Picard, Xuemin Shi, Michael Lazdunski
Abstract: The present invention provides compositions and methods for treating stroke patients using TCM and a Western medicament used for the treatment of stroke patients.
Type:
Application
Filed:
November 10, 2009
Publication date:
October 13, 2011
Applicant:
MOLEAC PTE. LTD.
Inventors:
David Picard, Shi Xuemin, Michael Lazdunski
Abstract: Methods which are useful to aid in smoking cessation. The methods generally comprise applying an electrical current to the subject in the vicinity of two or more acupuncture points selected from acupuncture points in or on the arms and hands of the subject. Suitable points include the Hegu acupuncture point (LI-4), a point on the opposite side of the hand to the Hegu acupuncture point, the Wai guan acupuncture point (SJ-5), and the Nei guan acupuncture point (PC-6).
Abstract: An apparatus for performing non-invasive stimulation of an animal's body, the apparatus comprising: a connector body having a conductor and a pair of stimulators electrically coupled to said conductor, the pair of stimulators being disposed on the connector body to allow the cutaneous surface of the animals body to be engaged therebetween. In use, a power source is electrically coupled to said conductor to transmit an electric current to the pair of stimulators to perform non-invasive stimulation on the animals body as current passes therethrough.
Type:
Application
Filed:
January 31, 2007
Publication date:
July 2, 2009
Applicant:
MOLEAC PTE LTD
Inventors:
Noor Indra Bin Sarif, Sze Tat Lim, Dennis Yu Guang Han, Derek Yong Tang Lim, Sharon Puay Ngee Goh, Henry Kok Wee Lim, Teck Leng Goh, Peer M. Sathikh, Leo Paul Louis, David Picard
Abstract: The present invention provides compositions and methods of treating a patient having a condition selected from the group of cerebral stroke, heart stroke, neurodegenerative diseases, brain or nervous system trauma, or neuroplasticity wherein the composition comprises: (i) at least 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 or 14 of: Radix Astragali (milkvetch root or Huang Qi); Rhizoma Salviae Miltiorrhizae root (red sage or Dan Shen); Radix Paeoniae Rubra (red peony or chi shao); Ligusticum Chuanxiong (Chuan Xiong); Rhizoma Notoginseng (Sanqi); Odoriferous Rosewood (Jiang Xiang); Scorpion (Quan Xie); Radix Polygalae (Yuan Zhi); Grassleaf sweetflag (Shi Changpu); Leech (Hirudo or Shuizhi); Ground beetle (Tu Bie Chong); Cow bezoar (calculus Bovis artifactus or Rengong Niuhuang); Gambirplant (ramulus uncariae cum uncis or Gou teng); and (ii) an agent used in Western medicine.
Type:
Application
Filed:
March 15, 2007
Publication date:
June 25, 2009
Applicant:
MOLEAC PTE. LTD
Inventors:
Xuemin Shi, Marie Germaine Bousser, David Picard