Patents Assigned to Molecular Cloning Laboratories (MCLAB) LLC
  • Compositions and methods for preparing sequencing libraries
    Patent number: 11274333
    Abstract: Compositions comprising activated topoisomerase adaptors (TOPO-adaptors) and methods of using the activated TOPO-adaptors are provided for preparing a library of target DNA duplexes derived from sample polynucleotides (e.g., DNA, RNA) for the streamlined preparation of a large number of samples. Such libraries may be used for Next Generation Sequencing (NGS).
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: March 15, 2022
    Assignee: Molecular Cloning Laboratories (MCLAB) LLC
    Inventors: Jianping Zheng, Changping Shi, Dan Shen, Thang Nguyen
  • Compositions and Methods for Preparing Sequencing Libraries
    Publication number: 20160348152
    Abstract: Compositions comprising activated topoisomerase adaptors (TOPO-adaptors) and methods of using the activated TOPO-adaptors are provided for preparing a library of target DNA duplexes derived from sample polynucleotides (e.g., DNA, RNA) for the streamlined preparation of a large number of samples. Such libraries may be used for Next Generation Sequencing (NGS).
    Type: Application
    Filed: May 26, 2016
    Publication date: December 1, 2016
    Applicant: Molecular Cloning Laboratories (MCLAB) LLC
    Inventors: Jianping Zheng, Changping Shi, Dan Shen, Thang Nguyen