Abstract: The present invention relates to novel agents that are useful for modulating transcription factor activity. In particular, the present invention relates to a transcription factor modulator comprising (i) a pharmaceutically-effective amount of a HLS-5 polypeptide, isoform thereof, functional fragment thereof or pharmaceutical composition thereof or (ii) a compound or composition capable of regulating the endogenous levels of HLS-5 or its activity; or (iii) combinations thereof.
Type:
Grant
Filed:
December 2, 2011
Date of Patent:
July 15, 2014
Assignee:
Molecular Discover Systems
Inventors:
Jean-Philippe Lalonde, Robin Scaife, S. Peter Klinken