Abstract: A system for optimising the cycling conditions used to control a polymerase chain reaction assigns membership values for denaturation, annealing and extension events in order to determine the relative contribution of each event during the reaction, and using genetic algorithms to determine the optimum times required to complete each event.
Type:
Grant
Filed:
March 31, 2000
Date of Patent:
December 10, 2002
Assignee:
Molecular Sensors Limited
Inventors:
John Michael Clarkson, Benjamin David Cobb