Patents Assigned to Molecule Probes, Inc.
  • Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules
    Patent number: 5773236
    Abstract: The subject invention describes compounds containing a polyhalogenated aryl moiety. The compounds of the invention are particularly useful for the assay of a variety of enzymes, including intracellular enzymes. The subject invention also describes assays for glutathione and/or glutathione transferase enzymes. Selected compounds of the invention are particularly useful for improving the retention of fluorescent products of enzyme metabolism in cells.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: June 30, 1998
    Assignee: Molecule Probes, Inc.
    Inventors: Zhenjun Diwu, Richard P. Haugland