Patents Assigned to Monolythix, Inc.
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Patent number: 10858690Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.Type: GrantFiled: May 25, 2017Date of Patent: December 8, 2020Assignee: Monolythix, Inc.Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
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Patent number: 10752937Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.Type: GrantFiled: July 28, 2017Date of Patent: August 25, 2020Assignee: MONOLYTHIX, INC.Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
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Patent number: 10570439Abstract: The present disclosure relates to a concentrator for concentrating, purifying or otherwise isolating one or more target analytes in a fluid matrix, and related methods, using self-wicking materials, such as monoliths. The present disclosure can be used as a point-of need sample preparation device. The self-contained device can be used for the extraction and concentration of specific target molecules, such as nucleic acids.Type: GrantFiled: August 18, 2016Date of Patent: February 25, 2020Assignees: Monolythix, Inc., Alfred E. Mann Foundation for Scientific ResearchInventors: Keith A. Oberg, Anthony Spence, Ivan Rueda, Mark D. Dobbs, Milton Lee
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Publication number: 20190338100Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.Type: ApplicationFiled: May 14, 2019Publication date: November 7, 2019Applicants: Monolythix, Inc., Alfred E. Mann Foundation for Scientific ResearchInventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
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Patent number: 10336881Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.Type: GrantFiled: September 28, 2016Date of Patent: July 2, 2019Assignees: Alfred E. Mann Foundation for Scientific Research, Monolythix, Inc.Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
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Publication number: 20170073492Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.Type: ApplicationFiled: September 28, 2016Publication date: March 16, 2017Applicants: Monolythix, Inc., Alfred E. Mann Foundation for Scientific ResearchInventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
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Publication number: 20170051273Abstract: The present disclosure relates to a concentrator for concentrating, purifying or otherwise isolating one or more target analytes in a fluid matrix, and related methods, using self-wicking materials, such as monoliths. The present disclosure can be used as a point-of need sample preparation device. The self-contained device can be used for the extraction and concentration of specific target molecules, such as nucleic acids.Type: ApplicationFiled: August 18, 2016Publication date: February 23, 2017Applicant: Monolythix, Inc.Inventors: Keith A. Oberg, Anthony Spence, Ivan Rueda, Mark D. Dobbs, Milton Lee
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Publication number: 20170051274Abstract: The present disclosure relates to a concentrator for concentrating, purifying or otherwise isolating one or more target analytes in a fluid matrix, and related methods, using self-wicking materials, such as monoliths. The present disclosure can be used as a point-of need sample preparation device. The self-contained device can be used for the extraction and concentration of specific target molecules, such as nucleic acids.Type: ApplicationFiled: August 18, 2016Publication date: February 23, 2017Applicant: Monolythix, Inc.Inventors: Keith A. Oberg, Anthony Spence, Ivan Rueda, Mark D. Dobbs, Milton Lee
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Patent number: 9464969Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.Type: GrantFiled: November 20, 2014Date of Patent: October 11, 2016Assignee: Monolythix, Inc.Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
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Publication number: 20160146714Abstract: Described herein are monoliths for processing fluid samples, and methods of making and using such monoliths.Type: ApplicationFiled: November 20, 2014Publication date: May 26, 2016Applicants: Monolythix, Inc., Alfred E. Mann Foundation for Scientific ResearchInventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee