Patents Assigned to Monolythix, Inc.
  • Patent number: 10858690
    Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: December 8, 2020
    Assignee: Monolythix, Inc.
    Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
  • Patent number: 10752937
    Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: August 25, 2020
    Assignee: MONOLYTHIX, INC.
    Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
  • Patent number: 10570439
    Abstract: The present disclosure relates to a concentrator for concentrating, purifying or otherwise isolating one or more target analytes in a fluid matrix, and related methods, using self-wicking materials, such as monoliths. The present disclosure can be used as a point-of need sample preparation device. The self-contained device can be used for the extraction and concentration of specific target molecules, such as nucleic acids.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: February 25, 2020
    Assignees: Monolythix, Inc., Alfred E. Mann Foundation for Scientific Research
    Inventors: Keith A. Oberg, Anthony Spence, Ivan Rueda, Mark D. Dobbs, Milton Lee
  • Publication number: 20190338100
    Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 7, 2019
    Applicants: Monolythix, Inc., Alfred E. Mann Foundation for Scientific Research
    Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
  • Patent number: 10336881
    Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: July 2, 2019
    Assignees: Alfred E. Mann Foundation for Scientific Research, Monolythix, Inc.
    Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
  • Publication number: 20170073492
    Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.
    Type: Application
    Filed: September 28, 2016
    Publication date: March 16, 2017
    Applicants: Monolythix, Inc., Alfred E. Mann Foundation for Scientific Research
    Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
  • Publication number: 20170051273
    Abstract: The present disclosure relates to a concentrator for concentrating, purifying or otherwise isolating one or more target analytes in a fluid matrix, and related methods, using self-wicking materials, such as monoliths. The present disclosure can be used as a point-of need sample preparation device. The self-contained device can be used for the extraction and concentration of specific target molecules, such as nucleic acids.
    Type: Application
    Filed: August 18, 2016
    Publication date: February 23, 2017
    Applicant: Monolythix, Inc.
    Inventors: Keith A. Oberg, Anthony Spence, Ivan Rueda, Mark D. Dobbs, Milton Lee
  • Publication number: 20170051274
    Abstract: The present disclosure relates to a concentrator for concentrating, purifying or otherwise isolating one or more target analytes in a fluid matrix, and related methods, using self-wicking materials, such as monoliths. The present disclosure can be used as a point-of need sample preparation device. The self-contained device can be used for the extraction and concentration of specific target molecules, such as nucleic acids.
    Type: Application
    Filed: August 18, 2016
    Publication date: February 23, 2017
    Applicant: Monolythix, Inc.
    Inventors: Keith A. Oberg, Anthony Spence, Ivan Rueda, Mark D. Dobbs, Milton Lee
  • Patent number: 9464969
    Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: October 11, 2016
    Assignee: Monolythix, Inc.
    Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
  • Publication number: 20160146714
    Abstract: Described herein are monoliths for processing fluid samples, and methods of making and using such monoliths.
    Type: Application
    Filed: November 20, 2014
    Publication date: May 26, 2016
    Applicants: Monolythix, Inc., Alfred E. Mann Foundation for Scientific Research
    Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee