Patents Assigned to Montigen Pharmaceuticals, Inc.
  • Protein Kinase Inhibitors
    Publication number: 20090099165
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: April 13, 2007
    Publication date: April 16, 2009
    Applicants: Arizona Board of Regents on Behalf of The University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence H. Hurley, Daruka Mahadevan, Haiyong Han, David J. Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Ruben M. Munoz, Steven L. Warner, Kimiko Della Croce, Daniel D. Von Hoff, Cory L. Grand, James Welsh
  • Substituted tricyclic compounds as protein kinase inhibitors
    Patent number: 7335662
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: February 26, 2008
    Assignees: Arizona Board of Regents on Behalf of the University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence H. Hurley, Daruka Mahadevan, David J. Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Steven L. Warner
  • Substituted tricyclic compound as protein kinase inhibitors
    Patent number: 7326713
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: February 5, 2008
    Assignees: Arizona board of Regents on Behalf of the University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence H. Hurley, Daruka Mahadevan, David J. Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Steven L. Warner
  • Substituted tricyclic compounds as protein kinase inhibitors
    Patent number: 7312226
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: December 25, 2007
    Assignees: Arizona Board of Regents on Behalf of The University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence H. Hurley, Daruka Mahadevan, David J. Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Steven L. Warner
  • Protein kinase inhibitors
    Publication number: 20050277658
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: March 29, 2005
    Publication date: December 15, 2005
    Applicants: Arizona Board of Regents on behalf of The University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence Hurley, Daruka Mahadevan, Haiyong Han, David Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Ruben Munoz, Steven Warner, Kimiko Della Croce, Daniel Von Hoff, Cory Grand
  • Protein kinase inhibitors
    Publication number: 20050239793
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: March 29, 2005
    Publication date: October 27, 2005
    Applicants: Arizona Board of Regents on behalf of The University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence Hurley, Daruka Mahadevan, Haiyong Han, David Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Ruben Munoz, Steven Warner, Kimiko Della Croce, Daniel Von Hoff, Cory Grand
  • Protein kinase inhibitors
    Publication number: 20050239794
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: March 29, 2005
    Publication date: October 27, 2005
    Applicants: Arizona Board of regents on behalf of the University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence Hurley, Daruka Mahadevan, Haiyong Han, David Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Ruben Munoz, Steven Warner, Kimiko Della Croce, Daniel Von Hoff, Cory Grand
  • Protein kinase inhibitors
    Publication number: 20050227992
    Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: October 14, 2004
    Publication date: October 13, 2005
    Applicants: Arizona Board of Regents on behalf of The University of Arizona, Montigen Pharmaceuticals, Inc.
    Inventors: Laurence Hurley, Daruka Mahadevan, Haiyong Han, David Bearss, Hariprasad Vankayalapati, Sridevi Bashyam, Ruben Munoz, Steven Warner, Kimiko Della Croce, Daniel Von Hoff, Cory Grand