Abstract: A method for repairing a perforation in a tympanic membrane comprising attaching a single patch to an undersurface of the tympanic membrane covering the perforation.
Abstract: The invention provides a method and a composition for the treatment of infants age less than 2.5 years old defined as small for gestational age (SGA), including the use of hGH or any compound that increases blood levels of hGH or of IGF-I. Early use of the composition prevents the irreversible neurological and psychological damage of the children.
Abstract: A method of preventing and/or treating S. pneumoniae infection in mammalian subjects, wherein said method comprises administering to said subjects a composition comprising one or more agents that are capable of inhibiting the binding of the S. pneumoniae cell wall protein FBA to the respiratory tract cells of said subject.
Type:
Grant
Filed:
September 29, 2008
Date of Patent:
November 5, 2013
Assignees:
Ben-Gurion University of the Negev Research and Development Authority, Mor Research Applications Ltd.
Abstract: A chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70% is disclosed. Further disclosed is a chitosan composition which forms a hydrogel at near physiological pH and 37° C., that includes at least one type of chitosan having a degree of deacetylation of at least about 70% and a molecular weight of from 10-4000 kDa, and at least one type of a chitosan having a molecular weight of from 200-20000 Da. Further disclosed are methods of preparation and uses of the chitosan compositions.
Type:
Application
Filed:
March 14, 2013
Publication date:
September 19, 2013
Applicant:
MOR RESEARCH APPLICATIONS LTD.
Inventors:
Noah Ben-Shalom, Zvi Nevo, Abraham Patchornik, Dror Robinson
Abstract: A method of analysis is disclosed. The method comprises: registering a target image to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image; accessing a database of registered and annotated images, and employing a polygon-wise comparison between the target image and each database image; and using the comparison for projecting annotated locations from the database images into the target image.
Type:
Application
Filed:
March 14, 2013
Publication date:
August 22, 2013
Applicants:
Ramot at Tel-Aviv University Ltd., Mor Research Applications Ltd.
Inventors:
Mor Research Applications Ltd., Ramot at Tel-Aviv University Ltd.
Abstract: An ocular implant including a hydrophobic pseudo-endothelial implant and a binding agent applied thereto, the binding agent capable of bonding the implant to a posterior portion of a cornea such that the implant serves as a water barrier enabling dehydration of the cornea.
Abstract: The present invention relates to prognostic methods and kits for the assessment and monitoring of relapse-free or disease-free survival of ALL patients. The detection is based on the use of detecting nucleic acids, specific for determination of the expression of at least one of miR-151-5p and miR-451 in a test sample. The invention thereby also provides methods and kits for monitoring and early diagnosis of cancerous disorders associated with low miR-151-5p and/or miR-451 expression, specifically ALL.
Abstract: The present invention provides combinations of an antipsychotic drug and a tetracycline, particularly minocycline, for the treatment of psychotic disorders, particularly schizophrenia. The invention also provides formulations wherein the release of one or both of the antipsychotic drug and the tetracycline is modified. The invention also provides methods using the combined therapy for treatment of psychotic disorders, particularly schizophrenia, comprising an antipsychotic drug and a tetracycline.
Abstract: This invention is directed, inter alia, to methods and kits for rapid, easy and cost-effective methods of breast cancer prediction and diagnosis in inter alia, blood samples.
Type:
Application
Filed:
October 24, 2012
Publication date:
July 25, 2013
Applicants:
Mor Research Application Ltd., Ben Gurion University of the Negev Research and Development Authority
Inventors:
Ben Gurion University of the Negev Research and, Mor Research Application Ltd.
Abstract: An embodiment of the invention provides a method of diagnosing obstructive sleep apnea, the method comprising: acquiring a sleep sound signal comprising sounds made by a person during sleep; detecting a plurality of snore sounds in the sleep sound signal; determining a set of mel-frequency cepstral coefficients for each of the snore sounds; determining a characterizing feature for the sleep sound signal responsive to a sum of the variances of the cepstral coefficients; and using the characterizing feature to diagnose obstructive sleep apnea in the person.
Type:
Application
Filed:
August 24, 2011
Publication date:
July 18, 2013
Applicants:
MOR RESEARCH APPLICATIONS LTD., BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
Inventors:
Yaniv Zigel, Ariel Tarasiuk, Nir Ben Israel
Abstract: The present: invention reveals a strong correlation between FGL-2 prothrombinase activity levels and the presence of a malignant proliferative disorder in a subject. Thus, the present invention provides FGL-2 prothrombinase activity as a diagnostic tool for malignancy.
Type:
Application
Filed:
July 11, 2011
Publication date:
May 9, 2013
Applicants:
RAMOT AT TEL-AVIV UNIVERSITY LTD., MOR RESEARCH APPLICATIONS LTD.
Abstract: Antisense oligonucleotides against cPLA2 are provided, which are capable of inhibiting cPLA2 expression as well as superoxide production, especially in phagocytes. These antisense oligonucleotides are powerful agents for the treatment of inflammatory conditions, in particular arthritis, as well as in neurodegenerative diseases. The antisense oligonucleotides or compositions comprising the same may be used in methods of treatment of such diseases.
Type:
Application
Filed:
July 12, 2012
Publication date:
November 1, 2012
Applicants:
Ben Gurion University of the Negev Research and Development Authority, Mor Research Applications Ltd.
Abstract: Monitoring system and method for use with diabetic treatment management. The system includes: a communication interface configured to permit access to stored raw log data, obtained over a certain time, being indicative of glucose measurements, meals consumed and insulin delivery; and a control unit including an unsupervised learning controller configured to receive and process said raw log data and determine at least one global insulin pump setting of basal rate, correction factor, carbohydrate ratio and insulin activity curve parameters. The system may include a processing unit including a first processor for processing measured data indicative of blood glucose level and generating first processed data, a second processor including at least one fuzzy logic module which receives input parameters corresponding to the measured data, the first processed data and a reference data, and processes the data to produce a qualitative output parameter to determine whether any treatment parameter should be modified.
Type:
Application
Filed:
March 29, 2012
Publication date:
September 27, 2012
Applicant:
MOR RESEARCH APPLICATIONS LTD.
Inventors:
Eran ATLAS, Revital NIMRI, Shahar MILLER, Eli Aviram GRUNBERG, Moshe PHILLIP
Abstract: Antisense oligonucleotides against cPLA2 are provided, which are capable of inhibiting cPLA2 expression as well as superoxide production, especially in phagocytes. These antisense oligonucleotides are powerful agents for the treatment of inflammatory conditions, in particular arthritis, as well as in neurodegenerative diseases. The antisense oligonucleotides or compositions comprising the same may be used in methods of treatment of such diseases.
Type:
Grant
Filed:
April 17, 2005
Date of Patent:
August 14, 2012
Assignees:
Mor Research Applications Ltd., Ben Gurion University of the Negev Research and Development Authority
Abstract: A method of analyzing a stream of imaging data is disclosed. The method comprises: for each picture-element of the data, associating a vector of features indicative of temporal intensity variation relative to baseline intensity, thereby providing a plurality of vectors. The method further comprises clustering the picture-elements according to the vectors, thereby providing a plurality of clusters, and identifying different compartments in the vasculature based on the clusters.
Type:
Application
Filed:
September 1, 2009
Publication date:
June 21, 2012
Applicants:
Mor Research Applications Ltd, Ben Gurion University Of The Negev Research and Development Authority
Inventors:
Alon Friedman, Yoash Chassidim, Ofer Psager, Ilan Shelef
Abstract: The present invention is directed to the field of cancer diagnosis, specifically to the diagnosis of bladder cancer (BC) and prostate cancer (CaP). More specifically, the invention provides simple, non-invasive urinary tests characterized by high sensitivity and specificity, wherein urinary levels of heat shock proteins and anti-inflammatory cytokines are used as biomarkers.
Type:
Application
Filed:
August 3, 2010
Publication date:
June 14, 2012
Applicants:
MOR - RESEARCH APPLICATIONS LTD., YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventors:
Irun R. Cohen, Meirav Pevsner-Fischer, David Margel, Jack Baniel, Ofer Yossepowitch
Abstract: A medical diagnosis decision support system for assisting a health professional to diagnose a medical condition. The system is first provided with an anchor condition that can be a symptom, a sign, a laboratory test result, or an imaging test results or any combination thereof The system then guides users in a series of predetermined phases regarding abstract or concrete diagnosis groups that should be considered and appropriate data that should be collected during the clinical investigation process. The system suggests history and physical examination clinical data items, laboratory, and imaging tests that should be collected in order to differentiate among alternative diagnoses. In each phase, possible diagnoses are listed and ranked.
Type:
Application
Filed:
April 14, 2010
Publication date:
October 20, 2011
Applicants:
CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD., MOR RESEARCH APPLICATIONS LTD.
Abstract: The present invention provides to a humanized monoclonal antibody having immunostimulatory effects. This antibody binds specifically to B lymphoblastoid cells, induces proliferation and activation of peripheral blood lymphocytes, particularly T cells, and is capable of eliciting an anti-tumor effect upon administration to subjects suffering from an immune deficiency.
Abstract: The present invention provides methods for treating specific populations of cancer patients by immunotherapy. The methods comprise administering an immunogenic composition eliciting an immune response to measles virus to patients having measles virus-immunoreactive cancer cells.
Type:
Application
Filed:
November 5, 2008
Publication date:
January 20, 2011
Applicant:
MOR RESEARCH APPLICATIONS LTD
Inventors:
Shmuel Ariad, Jacob Gopas, Daniel Benharroch, Irina Lazarev
Abstract: This invention is directed, inter alia, to methods and kits for rapid, easy and cost-effective methods of all free nucleic acid quantification in inter alia, biological fluid samples.