Patents Assigned to Morphochem Aktiengesellschaft für Kombinatorische Chemie
  • Oxazolidinone-quinolone hybrid antibacterials for the parenteral treatment or prophylaxis of bacterial diseases
    Patent number: 10723746
    Abstract: The present invention relates to the use of oxazolidinone-quinolone hybrids for the parenteral (especially intravenous) treatment or prophylaxis of bacterial diseases. The present invention relates moreover to improved methods of administering oxazolidinone-quinolone hybrid antibacterials.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: July 28, 2020
    Assignee: Morphochem Aktiengesellschaft Für Kombinatorische Chemie
    Inventors: Thomas Kapsner, Axel Dalhoff, Thomas Gramatte
  • OXAZOLIDINONE-QUINOLONE HYBRID ANTIBACTERIALS FOR THE PARENTERAL TREATMENT OR PROPHYLAXIS OF BACTERIAL DISEASES
    Publication number: 20160130288
    Abstract: The present invention relates to the use of oxazolidinone-quinolone hybrids for the parenteral (especially intravenous) treatment or prophylaxis of bacterial diseases. The present invention relates moreover to improved methods of administering oxazolidinone-quinolone hybrid antibacterials.
    Type: Application
    Filed: May 9, 2014
    Publication date: May 12, 2016
    Applicant: MORPHOCHEM AKTIENGESELLSCHAFT FÜR KOMBINATORISCHE CHEMIE
    Inventors: Thomas Kapsner, Axel Dalhoff, Thomas Gramatte
  • Oxazolidinone-quinolone hybrid antibiotics
    Patent number: 9133213
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: September 15, 2015
    Assignee: Morphochem Aktiengesellschaft Für Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Müller, Michael W. Cappi
  • Oxazolidinone-quinolone hybrid antibiotics
    Patent number: 8501774
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: August 6, 2013
    Assignee: Morphochem Aktiengesellschaft für Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Muller, Michael W. Cappi
  • USE OF OXAZOLIDINONE-QUINOLINE HYBRID ANTIBIOTICS FOR THE TREATMENT OF ANTHRAX AND OTHER INFECTIONS
    Publication number: 20120322766
    Abstract: The present invention relates to the use of compounds, in which the pharmacophores of quinolone and oxazolidinone are chemically linked together through a linker that is stable under physiological conditions, for the treatment of anthrax and other infections.
    Type: Application
    Filed: August 28, 2012
    Publication date: December 20, 2012
    Applicant: Morphochem Aktiengesellschaft fuer Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Hans Locher, Christine Schmitt
  • Intermediate products for producing oxazolidinone-quinolone hybrids
    Patent number: 8124772
    Abstract: The present invention describes intermediates (ZP) for a novel and efficient synthesis of compounds in which the pharmacophores of quinolone and oxazolidinone are linked to one another by way of a chemically stable linker.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: February 28, 2012
    Assignee: Morphochem Aktiengesellschaft für Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Jean Phillippe Surivet, Daniel Baeschlin
  • DUAL ACTION ANTIBIOTICS
    Publication number: 20110059946
    Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
    Type: Application
    Filed: September 10, 2010
    Publication date: March 10, 2011
    Applicant: Morphochem Aktiengesellschaft fuer Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin
  • Intermediate products for producing oxazolidinone-quinolone hybrids
    Patent number: 7557214
    Abstract: The present invention describes intermediates (ZP) for a novel and efficient synthesis of compounds in which the pharmacophores of quinolone and oxazolidinone are linked to one another by way of a chemically stable linker.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: July 7, 2009
    Assignee: Morphochem Aktiengesellschaft für Kombinatorische Chemie
    Inventors: Christian Hubschwerlen, Jean-Luc Specklin, Jean Phillippe Surivet, Daniel Baeschlin
  • Antibiotics for the treatment of infections in acidic environments
    Publication number: 20040132764
    Abstract: The present invention relates to the use of compounds, in which the pharmacophores of quinolone and oxazolidinone are chemically linked together through a linker that is stable under physiological conditions, for the treatment of bacterial infections in acidic environments (pH<7.0). The activity of these compounds is strongly increased at even slightly acidic conditions what makes them especially interesting for the treatment of infections in abscesses or inflamed tissues.
    Type: Application
    Filed: October 22, 2003
    Publication date: July 8, 2004
    Applicant: Morphochem Aktiengesellschaft fuer Kombinatorische Chemie
    Inventor: Hans Locher