Patents Assigned to Morphochem Aktiengesellschaft fur Kombinatorische Chemie
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Patent number: 10723746Abstract: The present invention relates to the use of oxazolidinone-quinolone hybrids for the parenteral (especially intravenous) treatment or prophylaxis of bacterial diseases. The present invention relates moreover to improved methods of administering oxazolidinone-quinolone hybrid antibacterials.Type: GrantFiled: May 9, 2014Date of Patent: July 28, 2020Assignee: Morphochem Aktiengesellschaft Für Kombinatorische ChemieInventors: Thomas Kapsner, Axel Dalhoff, Thomas Gramatte
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Publication number: 20160130288Abstract: The present invention relates to the use of oxazolidinone-quinolone hybrids for the parenteral (especially intravenous) treatment or prophylaxis of bacterial diseases. The present invention relates moreover to improved methods of administering oxazolidinone-quinolone hybrid antibacterials.Type: ApplicationFiled: May 9, 2014Publication date: May 12, 2016Applicant: MORPHOCHEM AKTIENGESELLSCHAFT FÜR KOMBINATORISCHE CHEMIEInventors: Thomas Kapsner, Axel Dalhoff, Thomas Gramatte
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Patent number: 9133213Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:Type: GrantFiled: July 2, 2013Date of Patent: September 15, 2015Assignee: Morphochem Aktiengesellschaft Für Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Müller, Michael W. Cappi
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Patent number: 8501774Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:Type: GrantFiled: February 8, 2012Date of Patent: August 6, 2013Assignee: Morphochem Aktiengesellschaft für Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Muller, Michael W. Cappi
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Patent number: 8329908Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:Type: GrantFiled: September 10, 2010Date of Patent: December 11, 2012Assignee: Morphochem Aktiengesellschaft fur Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin
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Publication number: 20120142635Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:Type: ApplicationFiled: February 8, 2012Publication date: June 7, 2012Applicant: Morphochem Aktiengesellschaft Fur Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Müller, Michael W. Cappi
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Publication number: 20120135961Abstract: The present invention relates to the use of compounds, in which the pharmacophores of quinolone and oxazolidinone are chemically linked together through a linker that is stable under physiological conditions, for the treatment of anthrax and other infections.Type: ApplicationFiled: January 10, 2011Publication date: May 31, 2012Applicant: Morphochem Aktiengesellschaft Fur Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Hans Locher, Christine Schmitt
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Patent number: 8158797Abstract: The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria.Type: GrantFiled: December 20, 2004Date of Patent: April 17, 2012Assignee: Morphochem Aktiengesellschaft fur Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Christine Schmitt, Stefan Müller, Michael W. Cappi
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Patent number: 8124772Abstract: The present invention describes intermediates (ZP) for a novel and efficient synthesis of compounds in which the pharmacophores of quinolone and oxazolidinone are linked to one another by way of a chemically stable linker.Type: GrantFiled: June 5, 2009Date of Patent: February 28, 2012Assignee: Morphochem Aktiengesellschaft für Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Jean Phillippe Surivet, Daniel Baeschlin
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Publication number: 20100324030Abstract: The present invention describes novel anti-bacterial compounds of the formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase and topoisomerases, for example of topoisomerase II and IV.Type: ApplicationFiled: April 11, 2008Publication date: December 23, 2010Applicant: Morphochem Aktiengesellschaft Fur Kombinatorische ChemieInventors: Glenn Dale, Sabine Pierau, Michael W. Cappi, Christopher Gray, Christian Hubschwerlen, Jean P. Surivet, Cornelia Zumbrunn
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Patent number: 7645782Abstract: The present invention relates to new Macrocycles of formula (I) and their use for the treatment of cancer.Type: GrantFiled: November 28, 2003Date of Patent: January 12, 2010Assignees: Morphochem Aktiengesellschaft fur Kombinatorische ChemieInventors: Wolfgang Richter, Lutz Weber
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Publication number: 20090306389Abstract: The present invention describes intermediates (ZP) for a novel and efficient synthesis of compounds in which the pharmacophores of quinolone and oxazolidinone are linked to one another by way of a chemically stable linker.Type: ApplicationFiled: June 5, 2009Publication date: December 10, 2009Applicant: Morphochem Aktiengesellschaft fur Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Jean Phillippe Surivet, Daniel Baeschlin
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Patent number: 7557214Abstract: The present invention describes intermediates (ZP) for a novel and efficient synthesis of compounds in which the pharmacophores of quinolone and oxazolidinone are linked to one another by way of a chemically stable linker.Type: GrantFiled: September 3, 2004Date of Patent: July 7, 2009Assignee: Morphochem Aktiengesellschaft für Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Jean Phillippe Surivet, Daniel Baeschlin
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Publication number: 20080051388Abstract: The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. Those compounds can be used in inhibiting factor Xa and in the prevention and/or treatment of thrombolytic conditions.Type: ApplicationFiled: July 19, 2005Publication date: February 28, 2008Applicant: Morphochem Aktiengesellschaft Fur Kombinatorische ChemieInventors: Thilo Fuchs, Robert Eckl
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Publication number: 20070244103Abstract: The present invention describes novel anti-bacterial compounds of formula (I). Q-A-R3??(I) These compounds are, amongst others, of interest as inhibitors of DNA gyrase.Type: ApplicationFiled: August 25, 2005Publication date: October 18, 2007Applicant: Morphochem Aktiengesellschaft Fur Kombinatorische ChemieInventors: Sabine Pierau, Glenn Dale, Michael Cappi, Cornelia Zumbrunn, Christian Hubschwerlen, Jean Surivet
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Publication number: 20070155714Abstract: The present invention relates to the use of compounds, in which the pharmacophores of quinolone and oxazolidinone are chemically linked together through a linker that is stable under physiological conditions, for the treatment of anthrax and other infections.Type: ApplicationFiled: April 6, 2004Publication date: July 5, 2007Applicant: Morphochem Aktiengesellschaft Fur Kombinatorische ChemieInventors: Christian Hubschwerlen, Jean-Luc Specklin, Daniel Baeschlin, Hans Locher, Christine Schmitt
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Publication number: 20060058389Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, hydrate or pharmaceutically acceptable formulation thereof. Those compounds can be used in inhibiting factor Xa and in the prevention and/or treatment of thromboembolic conditions.Type: ApplicationFiled: January 31, 2003Publication date: March 16, 2006Applicant: Morphochem Aktiengesellschaft fur Kombinatorische ChemieInventors: Robert Eckl, Silke Schabbert, Thilo Fuchs