Abstract: A process for the diagnosis of kidney diseases comprising the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, the polypeptide markers being selected from the markers characterized in Table 1 by values for the molecular masses and migration times.
Type:
Application
Filed:
November 15, 2013
Publication date:
March 13, 2014
Applicant:
Mosaiques Diagnostics and Therapeutics AG
Abstract: A method for the diagnosis of a benign or malignant bile duct stricture and/or of a CCC, comprising the step of determining at least three polypeptide markers in a body fluid, wherein the polypeptide marker belongs to those markers which in table 1 and/or table 2 a and/or b are characterized by values for the molecular mass and the migration time.
Type:
Application
Filed:
December 12, 2011
Publication date:
January 30, 2014
Applicant:
MOSAIQUES DIAGNOSTICS AND THERAPEUTICS AG
Abstract: Provided are a process and a device for the qualitative and/or quantitative determination of a protein and/or peptide pattern of a liquid sample taken from a human or animal body for checking its state. The peptides and proteins of the liquid sample are processed and then subjected to analysis, wherein reference and sample values describing states of a human or animal body as well as deviations and correspondences derived therefrom are established, automatically stored in a data base, and when the protein and/or peptide pattern is again determined, a search for optimum correspondence is automatically performed. In this process, mass components or structural components of the proteins and/or peptides are established and stored.
Type:
Grant
Filed:
January 27, 2004
Date of Patent:
June 7, 2011
Assignee:
Mosaiques Diagnostics and Therapeutics AG
Abstract: A method for the diagnosis of Alzheimer's disease, comprising the step of determining the presence or absence of at least one polypeptide marker in a sample, wherein the polypeptide marker is selected from markers 1 to 50 (frequency markers), or determining the amplitude of at least one polypeptide marker selected from markers 51 to 279 (amplitude markers)
Type:
Application
Filed:
April 5, 2006
Publication date:
February 11, 2010
Applicant:
MOSAIQUES DIAGNOSTICS AND THERAPEUTICS AG
Abstract: The invention relates to a method for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body. The proteins and peptides of the liquid sample are separated by capillary electrophoresis, then directly ionized and transferred for analysis online via an interface to a mass spectrometer coupled thereto.
Type:
Grant
Filed:
May 4, 2001
Date of Patent:
August 21, 2007
Assignee:
mosaiques diagnostics and therapeutics AG