Patents Assigned to MS Technologies
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Patent number: 11688264Abstract: A system and method for patient movement detection and fall monitoring to address the need to proactively monitor patients to detect abnormal movements, in-room activity, and other movements associated with providing in-room care. The system comprises an environmental model which can be used to track the position and movement of a patient and a classifier network configured to receive movement data and classify a patient's movement as normal or abnormal movement. In addition to monitoring in-room activity, the system and method create safe zones within the room to ensure patients are proactively monitor in the event of a seizure, fall, or other unintended activity. The system will record and store in-room video in a secure environment. Videos and notifications are automatically sent to designated staff as events occur.Type: GrantFiled: January 11, 2023Date of Patent: June 27, 2023Assignee: MS TECHNOLOGIESInventors: Shuchuan Jack Cheng, Yuan-Ming Fleming Lure
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Patent number: 11651672Abstract: A system and method for quantifying Alzheimer's disease (AD) risk using one or more interferometric micro-Doppler radars (IMDRs) and deep learning artificial intelligence to distinguish between cognitively unimpaired individuals and persons with AD based on gait analysis. The system utilizes IMDR to capture signals from both radial and transversal movement in three-dimensional space to further increase the accuracy for human gait estimation. New deep learning technologies are designed to complement traditional machine learning involving separate feature extraction followed-up with classification to process radar signature from different views including side, front, depth, limbs, and whole body where some motion patterns are not easily describable. The disclosed cross-talk deep model is the first to apply deep learning to learn IMDR signatures from two perpendicular directions jointly from both healthy and unhealthy individuals.Type: GrantFiled: November 22, 2022Date of Patent: May 16, 2023Assignee: MS TECHNOLOGIESInventors: Shuchuan Jack Cheng, Yuan-Ming Fleming Lure
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Patent number: 11651862Abstract: A system and method for predicting mild cognitive impairment (MCI) related diagnosis and prognosis utilizing deep learning. More specifically, the system and method produce predictions of MCI conversions to Alzheimer's/dementia and prognosis related thereof. Using available medical imaging and non-imaging data a diagnosis and prognosis model is a deep learned model trained using transfer learning. An MCI-DAP server may then receive a request from a clinician to process predictions related to a target patient's diagnosis or prognosis. The target patient's medical data is retrieved and used to create a model for the target patient. Then details of the target patient's model and the diagnosis and prognosis model are compared, a prediction is generated, and the prediction is returned to the clinician. As new medical data becomes available it is fed into the respective model to improve accuracy and update predictions.Type: GrantFiled: July 15, 2022Date of Patent: May 16, 2023Assignee: MS TECHNOLOGIESInventors: Yuan-Ming Fleming Lure, Jing Li, Teresa Wu, David Weidman, Kewei Chen, Xiaonan Liu, Yi Su
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Patent number: 11380181Abstract: A system for passively predicting and detecting falls using one or more dual-polarized Doppler radars and machine learning algorithms. The system is typically implemented for use in predicting or detecting falls in older adults and may be connected with various systems that can alert emergency services or hospice personnel in the event of a fallen individual. Furthermore, the system overcomes conventional radar systems by integrating vertical and horizontal micro-Doppler signatures into a combined signature which is analyzed by machine learning algorithms to correctly and expeditiously predict and detect a variety of human movements. The system also finds applications wherever micro-Doppler signals may be generated such as predicting or detecting behaviors or movements over time to detect and predict the onset of diseases and other disabilities.Type: GrantFiled: December 9, 2020Date of Patent: July 5, 2022Assignee: MS TECHNOLOGIESInventors: Shuchuan Jack Cheng, Yuan-Ming Fleming Lure
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Patent number: 10400250Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: GrantFiled: January 5, 2017Date of Patent: September 3, 2019Assignees: Dow AgroSciences LLC, MS Technologies, L.L.C.Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Patent number: 9540655Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: GrantFiled: December 2, 2011Date of Patent: January 10, 2017Assignees: Dow AgroSciences LLC, MS Technologies, L.L.C.Inventors: Yunxing Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn Parkhurst, Sandra Toledo, Terry Wright, Sean Russell, Bruce Held, Vaithilingam Sekar
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Patent number: 8648230Abstract: Regulatory regions are shown which regulate expression of an operably linked heterologous nucleic acid molecule in plants. Promoters are described which express at lower levels in pollen cells that in other plant cells. Methods of using such promoter to regulate expression of an operably linked nucleic acid molecule are described. A polyadenylation nucleotide sequence from soybean is further shown.Type: GrantFiled: March 18, 2011Date of Patent: February 11, 2014Assignee: MS Technologies, LLCInventors: Bruce Held, Vaithilingam Sekar, Janell C. Eby, Carol J. Lewnau, Penny Perkins
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Publication number: 20140041083Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: December 2, 2011Publication date: February 6, 2014Applicants: MS TECHNOLOGIES, LLC, DOW AGROSCIENCES LLCInventors: Yunxing Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn Parkhurst, Sandra Toledo, Terry Wright, Sean Russell, Bruce Held, Vaithilingam Sekar
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Publication number: 20130338006Abstract: This invention relates to soybean event pDAB8291.45.36.2, which includes a novel expression cassette comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding, and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to detection methods, including endpoint TaqMan PCR assays, for the detection of Event pDAB8291.45.36.2 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: December 2, 2011Publication date: December 19, 2013Applicants: MS TECHNOLOGIES, LLC, DOW AGROSCIENCES LLCInventors: Yunxing Cory Cui, Thomas Hoffman, Ning Zhou, Stephen Novak, Julissa Colon, Dawn M. Parkhurst, Sandra Grace Toledo, Terry R. Wright, Sean Michael Russell, Bruce Held, Vaithilingam Sekar
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Publication number: 20130055453Abstract: This invention relates to soybean event pDAB8264.42.32.1 and includes novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TAQMAN PCR assays for the detection of Event pDAB8264.42.32.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: July 13, 2012Publication date: February 28, 2013Applicants: MS TECHNOLOGIES, LLC, DOW AGROSCIENCES LLCInventors: Thomas Hoffman, Ning Zhou, Dayakar Pareddy, Yunxing Cory Cui, Dawn Marie Parkhurst, Nathan Bard, Sandra Grace Toledo, Gregory Alan Bradfisch, Bruce Held, Vaithilingam Sekar, Lauren Clark, Sean Michael Russell, Kelley Ann Smith, Yang Wang, Terry R. Wright
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Publication number: 20120240291Abstract: Regulatory regions are shown which regulate expression of an operably linked heterologous nucleic acid molecule in plants. Promoters are described which express at lower levels in pollen cells that in other plant cells. Methods of using such promoter to regulate expression of an operably linked nucleic acid molecule are described. A polyadenylation nucleotide sequence from soybean is further shown.Type: ApplicationFiled: March 18, 2011Publication date: September 20, 2012Applicant: MS TECHNOLOGIES, LLCInventors: Bruce Held, Vaithilingam Sekar, Janell Eby, Carol Lewnau, Penny Perkins
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Publication number: 20120144530Abstract: A nucleic acid molecule encoding a 5-enolpyruvyl-3-phosphoshikimic acid synthase (EPSPS) that provides resistance to glyphosate is provided, that has been optimized for expression in both monocotyledonous and dicotyledonous plants and preferably in soybeans. Methods of use are also provided.Type: ApplicationFiled: November 23, 2011Publication date: June 7, 2012Applicant: MS TECHNOLOGIES, LLCInventors: Bruce Held, Vaithilingam Sekar, Terry Wright, Sean Russell
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Patent number: 8153132Abstract: Antibodies immunoreactive to mutant Pseudomonas HPPD are provided, and in an embodiment the mutant HPPD is one in which the wild-type HPPD is substituted at residue 336 with tryptophan for glycine. Also provided are hybridomas producing the antibodies, as well as methods of making and using the antibodies.Type: GrantFiled: October 30, 2009Date of Patent: April 10, 2012Assignee: MS Technologies, Inc.Inventors: Vaithilingam Sekar, Bruce Held, Kyu Chung, Paul F. Russell, Jr.
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Publication number: 20110104755Abstract: Antibodies immunoreactive to mutant Pseudomonas HPPD are provided, and in an embodiment the mutant HPPD is one in which the wild-type HPPD is substituted at residue 336 with tryptophan for glycine. Also provided are hybridomas producing the antibodies, as well as methods of making and using the antibodies.Type: ApplicationFiled: October 30, 2009Publication date: May 5, 2011Applicant: MS TECHNOLOGIES, LLCInventors: Vaithilingam Sekar, Bruce Held, Kyu Chung, Paul F. Russell, JR.
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Patent number: 7888561Abstract: The invention is directed to a soybean polyubiquitin promoter, polyubiquitin terminator, sequences which hybridize to same and functional fragments thereof. The regulatory element of the invention provide improved expression in plants of operably linked nucleotide sequences. Expression vectors with the regulatory element is the subject of the invention, which may further include an operably linked nucleotide sequence. The invention is further directed to transformed plant tissue including the nucleotide sequence and to transformed plants and seeds thereof. The regulatory element is useful for driving a nucleotide sequence, for example a gene, or antisense expression or the like for the purpose of imparting agronomically useful traits such as, but not limited to, increase in yield, disease resistance, insect resistance, herbicide tolerance, drought tolerance and salt tolerance in plants.Type: GrantFiled: June 8, 2009Date of Patent: February 15, 2011Assignee: MS Technologies, LLCInventors: Vaithilingam Sekar, Carol Lewnau, Janell Eby, Brad Atchinson, Bruce Held
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Patent number: 7807791Abstract: Antibodies immunoreactive to double mutant EPSPS are provided, and in an embodiment the double mutant EPSPS is one in which the wild-type EPSPS is substituted at residue 102 with isoleucine and at residue 106 with serine. Also provided are hybridomas producing the antibodies, as well as methods of making and using the antibodies.Type: GrantFiled: September 17, 2008Date of Patent: October 5, 2010Assignee: MS Technologies LLCInventors: Vaithilingam Sekar, Bruce Held, Kyu Chung, Paul F. Russell, Jr.
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Publication number: 20100199377Abstract: The invention is directed to a soybean polyubiquitin promoter, polyubiquitin terminator, sequences which hybridize to same and functional fragments thereof. The regulatory element of the invention provide improved expression in plants of operably linked nucleotide sequences. Expression vectors with the regulatory element is the subject of the invention, which may further include an operably linked nucleotide sequence. The invention is further directed to transformed plant tissue including the nucleotide sequence and to transformed plants and seeds thereof. The regulatory element is useful for driving a nucleotide sequence, for example a gene, or antisense expression or the like for the purpose of imparting agronomically useful traits such as, but not limited to, increase in yield, disease resistance, insect resistance, herbicide tolerance, drought tolerance and salt tolerance in plants.Type: ApplicationFiled: June 8, 2009Publication date: August 5, 2010Applicant: MS TECHNOLOGIES, LLCInventors: Vaithilingam Sekar, Carol Lewnau, Janell Eby, Brad Atchinson, Bruce Held
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Patent number: 7667023Abstract: The invention is directed to a promoter, designated MuB, sequences which hybridize to same and functional fragments thereof. The regulatory element of the invention provide improved expression in plants of operably linked nucleotide sequences. Expression vectors with the regulatory element is the subject of the invention, which may further include an operably linked nucleotide sequence. The invention is further directed to transformed plant tissue including the nucleotide sequence and to transformed plants and seeds thereof. The regulatory element is useful for driving gene or antisense expression or the like for the purpose of imparting agronomically useful traits such as, but not limited to, increase in yield, disease resistance, insect resistance, herbicide tolerance, drought tolerance and salt tolerance in plants.Type: GrantFiled: October 30, 2007Date of Patent: February 23, 2010Assignee: MS TechnologiesInventors: Bruce Held, Vaithilingam Sekar, Janell Eby, Carol Lewnau, Sumei Xiong, Phil Dykema, Herbert Martin Wilson
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Publication number: 20090220999Abstract: Antibodies immunoreactive to double mutant EPSPS are provided, and in an embodiment the double mutant EPSPS is one in which the wild-type EPSPS is substituted at residue 102 with isoleucine and at residue 106 with serine. Also provided are hybridomas producing the antibodies, as well as methods of making and using the antibodies.Type: ApplicationFiled: September 17, 2008Publication date: September 3, 2009Applicant: MS TECHNOLOGIES, LLCInventors: Vaithilingam Sekar, Bruce Held, Kyu Chung, Paul F. Russell, JR.
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Publication number: 20090111186Abstract: The invention is directed to a promoter, designated MuB, sequences which hybridize to same and functional fragments thereof. The regulatory element of the invention provide improved expression in plants of operably linked nucleotide sequences. Expression vectors with the regulatory element is the subject of the invention, which may further include an operably linked nucleotide sequence. The invention is further directed to transformed plant tissue including the nucleotide sequence and to transformed plants and seeds thereof. The regulatory element is useful for driving gene or antisense expression or the like for the purpose of imparting agronomically useful traits such as, but not limited to, increase in yield, disease resistance, insect resistance, herbicide tolerance, drought tolerance and salt tolerance in plants.Type: ApplicationFiled: October 30, 2007Publication date: April 30, 2009Applicant: MS TECHNOLOGIES, LLCInventors: Bruce Held, Vaithilingam Sekar, Janell Eby, Carol Lewnau, Sumei Xiong, Phil Dykema, Herbert Martin Wilson