Abstract: A fluorous-modified composition, a fluorous nucleoside, nucleotide, or oligonucleotide microarray, a compositional detection process, a process of forming a fluorous nucleoside, nucleotide, or oligonucleotide microarray, and fluorous nucleoside, nucleotide, or oligonucleotide microarray processes are disclosed. The fluorous-modified composition includes a linker, a nucleoside, nucleotide, or oligonucleotide connected to the linker, and a fluorous domain connected to the linker. The fluorous-modified composition includes at least one terminal perfluoroalkyl group in the fluorous domain, a solid-phase attachment group connected to the linker, or a combination thereof. The compositional detection process includes using the fluorous microarray for compositional detection.

Abstract: A fluorous peptide microarray, a process of detecting information by using a fluorous peptide microarray, and a process of forming a fluorous peptide microarray are disclosed. The fluorous peptide microarray includes a covalently-modified conductive fluorous surface and fluorous-tagged peptides having natural amino acids positioned on the covalently-modified conductive fluorous surface. The fluorous-tagged peptides are configured for analysis of one or both of a protein and an enzyme. The process of detecting information includes using the fluorous peptide microarray. The process of forming the fluorous peptide microarray includes spotting the fluorous-modified composition to the fluorous surface after a solution phase reaction or transfer blotting the fluorous-modified composition.