Abstract: An energy-efficient and space-saving apparatus, arrangement, and method for managing vapor pressure difference in multilayered controlled-environment agriculture cultivation facilities includes a heating, ventilating, air conditioning, and dehumidification (HVACD) system. The HVACD system precisely controls temperature, humidity, and room vapor pressure of delivered air. The resulting air flow is also delivered locally, being directed downward and substantially perpendicular toward the canopy of the plants being cultivated. Speakers and/or vibration generators are also used to direct sounds and/or vibrations locally onto the canopy of the plants being cultivated, to break up the boundary layer on the surfaces of the leaves, to aid in the release of heat and humidity from the surfaces of the leaves into the surrounding air, for processing by the temperature and humidity control system.