Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.
Type:
Grant
Filed:
February 7, 2012
Date of Patent:
May 17, 2016
Assignee:
Multi-Sense Technologies Limited
Inventors:
Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.
Type:
Application
Filed:
February 7, 2012
Publication date:
January 16, 2014
Applicant:
MULTI-SENSE TECHNOLOGIES LIMITED
Inventors:
Phillip Lowe, Steven Alexander Keatch, Brian Mcguigan
Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.
Type:
Application
Filed:
September 7, 2011
Publication date:
November 21, 2013
Applicant:
MULTI-SENSE TECHNOLOGIES LIMITED
Inventors:
Phillip Lowe, Steven Alexander Keatch, Brian McGuigan