Patents Assigned to Multicell Technologies Inc.
  • Immortalized hepatocytes
    Patent number: 7566567
    Abstract: This invention relates to virally-immortalized hepatocyte cell lines, which are derived from a normal primary human liver cell, have the ability to proliferate in a serum-free media, are nontumorigenic, and produce proteins. These cell lines can be used for toxicity testing of potential therapeutic drugs and chemical entities. The cell lines may also be used for the production of therapeutic plasma proteins.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: July 28, 2009
    Assignee: Multicell Technologies Inc.
    Inventors: Jin Liu, Ronald A. Faris
  • Use of cell lines to produce active therapeutic proteins
    Publication number: 20070104696
    Abstract: This invention relates to the production of proteins, including therapeutic plasma proteins, by virally-immortalized hepatocyte cell lines and by other eukaryotic cells, as well as to the use of such proteins for screening and therapy, as well as to nucleic acids, vectors, and transformed or transfected cells that carry the genetic information for proteins.
    Type: Application
    Filed: October 7, 2004
    Publication date: May 10, 2007
    Applicant: Multicell Technologies, Inc.
    Inventors: Thomas Bush, Ronald Faris, Jin Liu
  • Immortalized hepatocytes
    Publication number: 20070004039
    Abstract: This invention relates to virally-immortalized hepatocyte cell lines, which are derived from a normal primary human liver cell, have the ability to proliferate in a serum-free media, are nontumorigenic, and produce proteins. These cell lines can be used for toxicity testing of potential therapeutic drugs and chemical entities. The cell lines may also be used for the production of therapeutic plasma proteins.
    Type: Application
    Filed: October 7, 2004
    Publication date: January 4, 2007
    Applicant: Multicell Technologies, Inc.
    Inventors: Jin Liu, Ronald Farie