Abstract: The present invention relates to stably episomally replicating vectors, comprising at least one scaffold/matrix attached region (S/MAR) and at least one viral or eukaryotic origin of replication (ORI), cells comprising these, processes for their preparation, and their use, in particular as a medicament or diagnostic.
Type:
Grant
Filed:
October 5, 1999
Date of Patent:
June 25, 2002
Assignee:
MultiGene Biotech GmbH Biozentrum am Hubland
Inventors:
Armin Baiker, Jürgen Bode, Christian Fetzer, Hans-Joachim Lipps, Christoph Piechaczek