Abstract: A sharps disposal system includes a holding chamber and a collecting chamber. The open bottom of the holding chamber is closed off by a bottom cover plate as sharps are accumulated. The bottom cover plate is confined by a locked articulated safety door which prevents accidental premature opening of the bottom of the holding chamber. When the accumulated sharps are to be removed from the holding chamber, the articulated safety door is unlocked and slid in a track from the bottom of holding chamber to the front wall. The collecting chamber is then inserted into the bottom of the holding chamber. The open top of the collecting chamber has a track holding a top cover plate. The top cover plate interlocks with the holding chamber bottom cover plate, and the two cover plates are withdrawn as a unit to allow the accumulated sharps to drop into the collecting chamber.