Patents Assigned to Multispan, Inc.
  • GPCR Expressing Cell Lines and Antibodies
    Publication number: 20120219968
    Abstract: The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
    Type: Application
    Filed: May 14, 2012
    Publication date: August 30, 2012
    Applicant: Multispan, Inc.
    Inventors: Helena S. Mancebo, Jeng-Horng Her, Samuel X. Li, Jianfu L. Wang
  • GPCR expression vector
    Patent number: 8178346
    Abstract: The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: May 15, 2012
    Assignee: Multispan, Inc.
    Inventors: Helena S. Mancebo, Jeng-Horng Her, Samuel X. Li, Jianfu L. Wang
  • GPCR Expressing Cell Lines and Antibodies
    Publication number: 20100330591
    Abstract: The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
    Type: Application
    Filed: June 22, 2010
    Publication date: December 30, 2010
    Applicant: Multispan, Inc.
    Inventors: Helena S. Mancebo, Jeng-Horng Her, Samuel X. Li, Jianfu L. Wang
  • GPCR-expressing cell lines
    Patent number: 7781209
    Abstract: The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: August 24, 2010
    Assignee: Multispan, Inc.
    Inventors: Helena S. Mancebo, Jeng-Horng Her, Samuel X. Li, Jianfu L. Wang
  • GPCR expressing cell lines and antibodies
    Publication number: 20070196867
    Abstract: The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
    Type: Application
    Filed: September 29, 2006
    Publication date: August 23, 2007
    Applicant: Multispan, Inc.
    Inventors: Helena Mancebo, Jeng-Horng Her, Samuel Li, Jianfu Wang